Development of Diagnostic Apparatus for Ear Disease

耳声发射（OAE）被认为起源于外毛细胞运动，并被认为以逆行方式通过中耳传输到外耳道。本文首先应用我们研制的扫频阻抗仪（SFI）和三种耳声发射测量仪，对人和豚鼠的中耳动力学特性和不同类型的耳声发射进行了测量，试图从多个方面探讨耳声发射与中耳动力学特性的关系，然后，对中耳动力学特性进行了研究。确定了一种同时诊断中耳和内耳疾病的仪器的测量方法，即在外耳道和鼓室压差最小时测量短纯音诱发的耳声发射，由于耳声发射测量方法的国际专利将在4年后到期，上述仪器的研制工作将在4年后开始。

Otoacoustic emissions (OAEs) are believed to originate from outer hair cell movement and are considered to be transmitted to the external auditory meatus through the middle ear in a retrograte fashion. Therefore, the effect of the middle ear on OAEs seems to be large.In this paper, firstly, applying our developed sweep frequency impedance meter (SFI) and three OAEs measuring apparatuses, middle ear dynamic characteristics and different sorts of OAEs of human subjects and guinea pigs were measured, and an attempt was made to examine the relationship between OAEs and middle ear dynamic characteristics from various aspects.Then, measurement method of an apparatus for diagnosing both middle and inner ear diseases is determined, i.e.tone-burst evoked OAEs are measured when the pressure difference between the external auditory meatus and the tympanic cavity is the smallest.As the international patent of the measuring method of OAEs will be expired in 4 years, the development of the apparatus mentioned above will start afterwards.