Development of Diagnostic Apparatus for Ear Disease
Development of Diagnostic Apparatus for Ear Disease
批准号:
05044148
负责人:
WADA Hiroshi
金额:
$1.28万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for international Scientific Research
财政年份:
1993
资助国家:
日本
项目状态:
已结题
起止时间:
1993 至 1994
中文摘要
耳声发射(OAEs)被认为起源于外毛细胞的运动,并被认为是以退行性的方式通过中耳传递到外耳道。本文首先应用自行研制的扫频阻抗测试仪和三种耳声发射测量仪,对受试者和豚鼠的中耳动态特性和不同类型的耳声发射进行了测量,从不同角度探讨了中耳声学特性与中耳动态特性的关系。在此基础上,确定了中耳和内耳疾病诊断仪的测量方法。即在外耳道与鼓室之间的压差最小时测量短纯音诱发的耳声发射,由于该测量方法的国际专利将在4年后到期,上述仪器的研制将随之展开。
英文摘要
Otoacoustic emissions (OAEs) are believed to originate from outer hair cell movement and are considered to be transmitted to the external auditory meatus through the middle ear in a retrograte fashion. Therefore, the effect of the middle ear on OAEs seems to be large.In this paper, firstly, applying our developed sweep frequency impedance meter (SFI) and three OAEs measuring apparatuses, middle ear dynamic characteristics and different sorts of OAEs of human subjects and guinea pigs were measured, and an attempt was made to examine the relationship between OAEs and middle ear dynamic characteristics from various aspects.Then, measurement method of an apparatus for diagnosing both middle and inner ear diseases is determined, i.e.tone-burst evoked OAEs are measured when the pressure difference between the external auditory meatus and the tympanic cavity is the smallest.As the international patent of the measuring method of OAEs will be expired in 4 years, the development of the apparatus mentioned above will start afterwards.
期刊论文(2)
专著(0)
科研奖励(0)
会议论文
Hiroshi Wda: "Middle Ear Effect on Otoacoustic Emissions" Audiology. (発表予定).
Hiroshi Wda:“中耳对耳声发射的影响”听力学(待公布)。
DOI:
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发表时间:
期刊:
影响因子:
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作者:
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通讯作者:
Hiroshi Wada: "Middle Ear Effect on Otoacoustic Emissions" Audiology. (Presentation Scheduled).
Hiroshi Wada:“中耳对耳声发射的影响”听力学。
DOI:
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发表时间:
期刊:
影响因子:
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作者:
[]
通讯作者:
Challenges of visualizing the conformational changes of prestin using an atomic force microscope equipped with a membrane potential control device
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批准号:23659790
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项目类别:Grant-in-Aid for Challenging Exploratory Research
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资助金额:$2.41万
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财政年份:2011
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负责人:WADA Hiroshi
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依托单位:
Correlation between expression of exocrine progenitor genes and cancer stem cells in pancreatic cancer.
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财政年份:2010
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Molacular evolutionary background of the innovations of deuterostome morphologo
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批准号:21370105
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项目类别:Grant-in-Aid for Scientific Research (B)
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财政年份:2009
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Ring-shaped chalkiness increased by dry wind in rice : Direct measurement of turgor in endosperm cells and the role of osmotic adjustment at low water potential
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批准号:21380017
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$12.73万
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财政年份:2009
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Creation of a New Method to Refold the Membrane Protein Mutants for Curing of Hereditary Hearing Loss
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批准号:20390439
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$12.23万
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财政年份:2008
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负责人:WADA Hiroshi
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依托单位:
Structural and functional analysis of the motor protein prestin using purified protein
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批准号:18390455
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$10.48万
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财政年份:2006
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负责人:WADA Hiroshi
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依托单位:
Structural analysis of the motor protein prestin
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批准号:15086202
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项目类别:Grant-in-Aid for Scientific Research on Priority Areas
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资助金额:$26.24万
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财政年份:2003
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负责人:WADA Hiroshi
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依托单位:
Biomechanics at Micro- and Nanoscale Levels
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批准号:15086101
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项目类别:Grant-in-Aid for Scientific Research on Priority Areas
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资助金额:$13.89万
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财政年份:2003
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负责人:WADA Hiroshi
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依托单位:
Research on construction of a theory about redevelopment of the exhibition and preservation space for the cultural property in a historic buildings.
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批准号:14209021
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项目类别:Grant-in-Aid for Scientific Research (A)
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资助金额:$30.2万
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财政年份:2002
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负责人:WADA Hiroshi
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依托单位:
Research on evolution of larval skeleton in sea urchin: Echinometridae
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批准号:13839008
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.3万
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财政年份:2001
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负责人:WADA Hiroshi
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依托单位:
Development of the program for analysis of the dynamic behavior of the organ of Corti
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批准号:13557142
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$8.7万
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财政年份:2001
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负责人:WADA Hiroshi
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依托单位:
Analysis of the function of the protein motor within the outer hair cell motility
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批准号:11307033
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项目类别:Grant-in-Aid for Scientific Research (A).
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资助金额:$24.83万
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财政年份:1999
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负责人:WADA Hiroshi
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依托单位:
Determination of OHC protein motor
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批准号:11694236
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项目类别:Grant-in-Aid for Scientific Research (B).
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资助金额:$4.03万
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财政年份:1999
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负责人:WADA Hiroshi
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依托单位:
Development of hand-guided measurement device of stapes mobility using the micromachining technique
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批准号:11557124
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$6.4万
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财政年份:1999
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负责人:WADA Hiroshi
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依托单位:
A comprehensive study about the eunuchs in the Byzantine society
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批准号:10610372
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$1.66万
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财政年份:1998
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负责人:WADA Hiroshi
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依托单位:
Vibration measurement of the tympanic membrane using electronic speckle pattern interferometry
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批准号:07557107
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项目类别:Grant-in-Aid for Scientific Research (A)
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资助金额:$12.48万
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财政年份:1995
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负责人:WADA Hiroshi
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依托单位:
Analysis of isolated outer hair cell motility in response to sound stimuli using high speed video system.
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批准号:06404060
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项目类别:Grant-in-Aid for General Scientific Research (A)
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资助金额:$18.5万
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财政年份:1994
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负责人:WADA Hiroshi
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依托单位:
Development of measurement system for basilar membrane vibrations using a laser Doppler vibrometer coupled to a microscope.
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批准号:04557074
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项目类别:Grant-in-Aid for Developmental Scientific Research (B)
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资助金额:$6.21万
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财政年份:1992
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负责人:WADA Hiroshi
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依托单位:
Development of Animated Expression of Eardrum Vibration
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批准号:02557064
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项目类别:Grant-in-Aid for Developmental Scientific Research (B)
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资助金额:$3.33万
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财政年份:1990
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负责人:WADA Hiroshi
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依托单位:
Structure and Functions of the Central Histaminergic Neuron System
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批准号:63065004
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项目类别:Grant-in-Aid for Specially Promoted Research
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资助金额:$111.36万
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财政年份:1988
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负责人:WADA Hiroshi
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依托单位: