The development of monochromatic X-ray computed tomography with synchrotron radiation
同步辐射单色X射线计算机断层扫描的发展
基本信息
- 批准号:05404037
- 负责人:
- 金额:$ 21.25万
- 依托单位:
- 依托单位国家:日本
- 项目类别:Grant-in-Aid for General Scientific Research (A)
- 财政年份:1993
- 资助国家:日本
- 起止时间:1993 至 1994
- 项目状态:已结题
- 来源:
- 关键词:
项目摘要
For biomedical diagnosis, a new monochromatic x-ray CT system using synchrotron radiation is being developed to obtain clear images and to detect low contrast materials for quantitative functional evaluation of organs in correspondence with their anatomical structures.The SR-CT system is constructed at the beam line NE-5A of the Tristan Accumulation Ring in Tsukuba (6.5GeV,20-30mA). This system consists of a rotating x-ray shutter, a silicon (111) and silicon (511) double monochromator, an x-ray slits system, a roating object table, an x-ray linear array sensor system and a computer. By this system, the image with x-ray energy from 30 to 52 keV can be obtained to detect various contrast materials (iodine, barium and gadolinum). The x-ray linear arry sensor consists of BGO scintillators and a silicon photo-diode array. The dynamic range of the system is 60000 : 1 with 200mum of the spatial resolution. Image data was digitized by a 16 bit A/D converter and led to the computer. Exposure time of each projection can be changed from 3 ms to longer. Slice thickness of the object can be also adjustable from 0.1 to 3.2 mm using the slit system. Using a unix workstation, a SR-CT image is reconstructed from the line data obtained by x-ray linear array detector. This workstation can perform high speed image reconstruction using graphic accelerator board.Using the double crystal monochromator, the high order x-ray contamination is eliminated. A new CCD detector have some problems at the junction of sensor, and this produced the artifact. As the machine trouble of AR ring occurred in 1994, the experiments of this system could not performed sufficiently. The detailed experiment will be performed in 1995.
在生物医学诊断方面,一种新的同步辐射单色X射线CT系统正在研制中,该系统是在Tristan积累环NE-5A(6.5GeV,20 - 30 mA)的束线上建造的。该系统由旋转X光快门、硅(111)和硅(511)双单色器、X光狭缝系统、旋转载物台、X光线阵传感器系统和计算机组成。该系统可获得能量为30 ~ 52 keV的X射线图像,用于检测各种造影剂(碘、钡、钆)。X射线线阵传感器由BGO晶体管和硅光电二极管阵列组成。系统的动态范围为60000:1,空间分辨率为200 μ m。图像数据经16位A/D转换器数字化后送入计算机。每个投影的曝光时间可以从3 ms到更长。使用狭缝系统,物体的切片厚度也可以在0.1至3.2 mm之间调节。利用X射线线阵探测器获得的线阵数据,在UNIX工作站上重建SR-CT图像。该工作站利用图形加速板进行高速图像重建,利用双晶单色器消除了高次X射线污染。一种新的CCD探测器在传感器的连接处出现了一些问题,从而产生了伪影。由于1994年AR环发生机械故障,该系统的实验不能充分进行。详细的实验将于1995年进行。
项目成果
期刊论文数量(9)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
Umetani K,Ueda K,Takeda T,Anno I,Itai Y,Akisada M: "Two-dimensional real-time imaging system for subtraction angiography using an iodine filter" Rev.Sci.Instrum.63 (1). 629-631 (1992)
Umetani K,Ueda K,Takeda T,Anno I,Itai Y,Akisada M:“使用碘滤光片进行减影血管造影的二维实时成像系统”Rev.Sci.Instrum.63(1)。
- DOI:
- 发表时间:
- 期刊:
- 影响因子:0
- 作者:
- 通讯作者:
武田徹: "放射光を利用した微量元素分析型CT開発" 新医療. 230. 72-76 (1994)
Toru Takeda:“使用同步加速器辐射进行微量元素分析的 CT 的开发”《新医学》230. 72-76 (1994)。
- DOI:
- 发表时间:
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- 影响因子:0
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- 通讯作者:
Itai Y.,Ohtomo K.: "Clinical application of computed tomography in the liver." Georg Thieme,Stutugart., (1993)
Itai Y.,Ohtomo K.:“计算机断层扫描在肝脏中的临床应用。”
- DOI:
- 发表时间:
- 期刊:
- 影响因子:0
- 作者:
- 通讯作者:
武田徹: "放射光CTの開発動向" Med.Imag.Tech.11. 621-627 (1993)
武田彻:“同步辐射CT的发展趋势”Med.Imag.Tech.11(1993)。
- DOI:
- 发表时间:
- 期刊:
- 影响因子:0
- 作者:
- 通讯作者:
Takeda T: "High spatial resolution CT with a synchrotron radiation system." Journal of Computer Assisted Tomography. 18. 98-101 (1994)
Takeda T:“具有同步辐射系统的高空间分辨率 CT。”
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- 影响因子:0
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{{ truncateString('ITAI Yuji', 18)}}的其他基金
Development of high-sensitive synchrotron x-ray micro CT
高灵敏同步加速器X射线显微CT的研制
- 批准号:
12307018 - 财政年份:2000
- 资助金额:
$ 21.25万 - 项目类别:
Grant-in-Aid for Scientific Research (A)
Development of phase contrast x-ray imaging system
相衬X射线成像系统的研制
- 批准号:
08407024 - 财政年份:1996
- 资助金额:
$ 21.25万 - 项目类别:
Grant-in-Aid for Scientific Research (A)
Development of CT to simultanously detect scattering x-ray, fluorescent x-ray and transmission x-ray
开发同时检测散射X射线、荧光X射线和透射X射线的CT
- 批准号:
06507002 - 财政年份:1994
- 资助金额:
$ 21.25万 - 项目类别:
Grant-in-Aid for Developmental Scientific Research (A)
Research on MRI Contrast Agents for the Liver.
肝脏 MRI 造影剂的研究。
- 批准号:
02454282 - 财政年份:1990
- 资助金额:
$ 21.25万 - 项目类别:
Grant-in-Aid for General Scientific Research (B)
Diagnosis and evaluation of hepatocellular carcinoma and precancerous states using magnetic resonance imaging
磁共振成像对肝细胞癌及癌前状态的诊断和评估
- 批准号:
60480254 - 财政年份:1985
- 资助金额:
$ 21.25万 - 项目类别:
Grant-in-Aid for General Scientific Research (B)
相似海外基金
In-cell synthesis of anticancer drugs from non-toxic precursor compounds by monochromatic X-ray irradiation
通过单色X射线照射从无毒前体化合物细胞内合成抗癌药物
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25670541 - 财政年份:2013
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$ 21.25万 - 项目类别:
Grant-in-Aid for Challenging Exploratory Research
A syringe-needle type monochromatic X-ray source for selective tumor irradiation using X-ray absorption characteristics of sensitizing agents
利用敏化剂X射线吸收特性进行选择性肿瘤照射的注射针式单色X射线源
- 批准号:
24650291 - 财政年份:2012
- 资助金额:
$ 21.25万 - 项目类别:
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Development of application of compact tunable monochromatic X-ray source
紧凑型可调谐单色X射线源的应用进展
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17360454 - 财政年份:2005
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Quasi-monochromatic X-ray Source for Mammography
用于乳腺X线摄影的准单色X射线源
- 批准号:
6669658 - 财政年份:2002
- 资助金额:
$ 21.25万 - 项目类别:
Quasi-monochromatic X-ray Source for Mammography
用于乳腺X线摄影的准单色X射线源
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6486321 - 财政年份:2002
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Development of the oscillation system for a micro-are monochromatic X-ray diffractometer.
微弧单色X射线衍射仪振荡系统的研制。
- 批准号:
14540453 - 财政年份:2002
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$ 21.25万 - 项目类别:
Grant-in-Aid for Scientific Research (C)
Development of in-house microangiography using high-intensity quasi-monochromatic x-ray Irradiation from the linear plasma target
使用线性等离子体靶的高强度准单色 X 射线照射开发内部微血管造影术
- 批准号:
13470154 - 财政年份:2001
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$ 21.25万 - 项目类别:
Grant-in-Aid for Scientific Research (B)
QUASI-MONOCHROMATIC X-RAY SOURCE FOR MAMMOGRAPHY
用于乳房X线照相术的准单色X射线源
- 批准号:
6140973 - 财政年份:2000
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