Development of spiral-vortex-type blood pump (Optimal design and its application to cardiomyoplasty)

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A spiral-vortex-type blood pump is one of the promising pumps having the best fluid dynamic characteristics to control the thrombus formation inside the pump. To develop a total system of the pump and for an application of it to the cardiomyoplasty, following studies have been conducted.(1) A new system for the measurement of pump flow was designed, based on a principle that the electrical capacitance of electrodes attached to the pump surface changes depending on the blood volume inside the pump. A preliminary test in vitro has shown excellent results.(2) An economical method for the fabrication of the blood pump has been designed, using vacuum forming and injection molding. Using the technique, several pumps with different physical shapes were fabricated, and basic performance of them has been tested and compared with each others for the empirical optimization of pump shape.(3) A new economical ball valve with plastic housing has been designed for the blood pump application. A preliminary test in vitro has proven an excellent fluid dynamical performance of the valve.(4) Effect of rough surface of polymer materials on the thrombogenisity have been analyzed quantitatively. The surface of the polymer was fabricated quantitatively textured (physical length and interval) with laser beam, and the polymer has been implanted in sheep. The experiments are still on the way.(5) Basic mechanical characteristics (energetics) of the pump diaphragm have been analyzed for the future application of cardiomyoplasty.(6) Flow pattern inside the pump has been measured by laser Doppler anemometry. The analyzing software has been developed, and the results have been displayd in animation.(7) Acute animal experiments have been conducted for test the feasibility of blood pump system. The pumps have shown excellent spiral-vortex inside the pump.