IDENTIFICATION OF LIFE CYCLE AND ESTABLISHMENT OF THE METHOD FOR DlAGNOSIS,PREVENTION AND TREATMENT OF NEOSPORA CANINUM
犬新孢子虫生命周期的鉴定及诊断、防治方法的建立
基本信息
- 批准号:07556070
- 负责人:
- 金额:$ 12.67万
- 依托单位:
- 依托单位国家:日本
- 项目类别:Grant-in-Aid for Scientific Research (A)
- 财政年份:1995
- 资助国家:日本
- 起止时间:1995 至 1997
- 项目状态:已结题
- 来源:
- 关键词:
项目摘要
1.Study on the incidence of neo sporosis in Japan : the disease occurred in 24 prefectures so far and distributed widely throughout the country. The earliest occurrence of the disease was in 1985, and many cattle imported from USA had the antibody against the protozoa. Shelty dogs and dogs kept with cattle frequently had the antibody. Based on these results, a circulation of the protozoa among dogs and cattle was suspected and we recommended farmers not to keep dogs with cattle.2.Isolation of neospora : weisolated 8 strains of neospora from aborted fetuses or congenitally-infected newborn calves in Japan. Ribosomal DNA of our isolates was identical with those isolaed in USA.Antigen plates for fluorescent antibody test and latex beads ELISA kit were prepared using our isolales.3.Study on the mode of transmission : antibody against the protozoa was sought in various animals (dogs, cats, mice, pigeons and racoons) habitaing near the affected cattle, and none of them except dogs had the antibody. Nude mice experimentally infected with the protozoa showed radiculoneuritis and a proliferation of the parasites in the digestive tract. These findings suggested the a possible vertical transmission of neospora by the feces excreted from infected animals.
1.日本新孢子虫病发病率研究:迄今为止,该病在24个都道府县发生,在全国广泛分布。该病最早发生于1985年,从美国进口的牛中有大量的抗原虫抗体。舍饲犬和与牛饲养的犬经常有抗体。根据这些结果,我们怀疑原生动物在狗和牛之间循环,我们建议农民不要将狗与牛一起饲养。2.新孢子虫的分离:我们从日本流产的胎儿或先天性感染的新生小牛中分离到8株新孢子虫。3.传播方式的研究:在病牛附近的动物(狗、猫、小鼠、鸽子和浣熊)中均检测到抗原虫抗体,除狗外均无抗体。实验性感染这种原虫的裸鼠表现出神经根炎和消化道寄生虫的增殖。这些结果表明,新孢子虫可能通过感染动物的粪便垂直传播。
项目成果
期刊论文数量(48)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
播谷 亮: "牛のネオスポラ症" 動物の原虫病. 10. 1-5 (1997)
Ryo Hariya:“牛新孢子虫病”动物原生动物疾病。10. 1-5 (1997)
- DOI:
- 发表时间:
- 期刊:
- 影响因子:0
- 作者:
- 通讯作者:
Sawada, M., Park, C.-H., Kondo, H., Morita, T., Shimada, A., Yamane, I.and Umemura, T.: "Serological survey of antibody to Neospora caninum in Japanese dogs." Journal of Veterinary Medical Science. (in press). (1998)
Sawada, M.、Park, C.-H.、Kondo, H.、Morita, T.、Shimada, A.、Yamane, I. 和 Umemura, T.:“日本犬新孢子虫抗体的血清学调查。
- DOI:
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- 影响因子:0
- 作者:
- 通讯作者:
Haritani, M.: "Abortion of cows due to Neospora." Kachikushinryo. 399 (in Japanese).33-34 (1996)
Haritani, M.:“由于新孢子虫导致的奶牛流产。”
- DOI:
- 发表时间:
- 期刊:
- 影响因子:0
- 作者:
- 通讯作者:
Haritani, M.: "Bovine neosporosis." Fonus. 16 (in Japanese).1-6 (1996)
Haritani, M.:“牛新孢子虫病。”
- DOI:
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- 期刊:
- 影响因子:0
- 作者:
- 通讯作者:
I.Yamane: "In vitro isolation and characterization of the bovine Neospora sp in Japan" Research is Veterinary Science. (in press). (1997)
I.Yamane:“日本牛新孢子虫的体外分离和表征”研究是兽医科学。
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- 影响因子:0
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UMEMURA Takashi其他文献
Present Studies in manuscripts of "Owarinokuni Gunji Hyakushou rano Gebumi
《尾张之国军师百胜乱纪文》手稿的现况研究
- DOI:
- 发表时间:
2005 - 期刊:
- 影响因子:0
- 作者:
NAKANISHI;Yuji;UMEMURA Takashi - 通讯作者:
UMEMURA Takashi
ISHIMODA Sho's Theory of "Localism" and Studies of Ancient and Medieval Japan
石茂田翔的“地方主义”理论与日本古代和中世纪研究
- DOI:
- 发表时间:
2005 - 期刊:
- 影响因子:0
- 作者:
NAKAGAWA;Yuri;UMEMURA Takashi - 通讯作者:
UMEMURA Takashi
UMEMURA Takashi的其他文献
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{{ truncateString('UMEMURA Takashi', 18)}}的其他基金
Treatment of rebies using intratheal immunization and the mechanisms of the treatment
鞘内免疫治疗雷比斯及其治疗机制
- 批准号:
23380171 - 财政年份:2011
- 资助金额:
$ 12.67万 - 项目类别:
Grant-in-Aid for Scientific Research (B)
Pathogenesis of influenza virus-associated encephalopathy of childhood induced in animal model
动物模型诱导的儿童流感病毒相关性脑病的发病机制
- 批准号:
23658250 - 财政年份:2011
- 资助金额:
$ 12.67万 - 项目类别:
Grant-in-Aid for Challenging Exploratory Research
Land notarization documents and assumption research on place territory relief in the Heian era
平安时代土地公证文书及地方疆域救济设想研究
- 批准号:
19520569 - 财政年份:2007
- 资助金额:
$ 12.67万 - 项目类别:
Grant-in-Aid for Scientific Research (C)
Establishment of novel preventive/therapeutic measures and demonstration of a mechanism of neural spread of pathogens in neurotropic zoonotic diseases
建立新型预防/治疗措施并论证嗜神经性人畜共患疾病病原体的神经传播机制
- 批准号:
19380171 - 财政年份:2007
- 资助金额:
$ 12.67万 - 项目类别:
Grant-in-Aid for Scientific Research (B)
The research of a lawsuit documents and related historical materials at the Heian era
平安时代诉讼文书及相关史料研究
- 批准号:
14310156 - 财政年份:2002
- 资助金额:
$ 12.67万 - 项目类别:
Grant-in-Aid for Scientific Research (B)
PATHOGENESIS OF INFLUENZAL ENCEPHALITIS/ENCEPHALOPATHY
流感脑炎/脑病的发病机制
- 批准号:
14360182 - 财政年份:2002
- 资助金额:
$ 12.67万 - 项目类别:
Grant-in-Aid for Scientific Research (B)
Experimental Reproduction of itai-itai disease in cynomolgus monkeys
食蟹猴痛痛病的实验复制
- 批准号:
10460136 - 财政年份:1998
- 资助金额:
$ 12.67万 - 项目类别:
Grant-in-Aid for Scientific Research (B).
Pathogenicity and its mechanism of Mycoplasma hyorhinis
猪鼻支原体的致病性及其机制
- 批准号:
08456159 - 财政年份:1996
- 资助金额:
$ 12.67万 - 项目类别:
Grant-in-Aid for Scientific Research (B)
Porcine otitis is a novel mycoplasmal disease
猪中耳炎是一种新型支原体病
- 批准号:
06454130 - 财政年份:1994
- 资助金额:
$ 12.67万 - 项目类别:
Grant-in-Aid for General Scientific Research (B)
The Development of "Sho" in the Heian Peviod
平安时代“翔”的发展
- 批准号:
06610317 - 财政年份:1994
- 资助金额:
$ 12.67万 - 项目类别:
Grant-in-Aid for General Scientific Research (C)
相似海外基金
Global study using fluorescent Neospora caninum on the vertical transmission mechanism in neosporosis
使用荧光犬新孢子虫研究新孢子虫病垂直传播机制的全球研究
- 批准号:
22580342 - 财政年份:2010
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$ 12.67万 - 项目类别:
Grant-in-Aid for Scientific Research (C)
Characterization of abortion related factor of intracellular protozoan parasite Neospora caninum and its application for vaccine development
细胞内原生动物寄生虫犬新孢子虫流产相关因子的表征及其在疫苗开发中的应用
- 批准号:
21780262 - 财政年份:2009
- 资助金额:
$ 12.67万 - 项目类别:
Grant-in-Aid for Young Scientists (B)
Proteomic analysis of the invading mechanism of Neospora caninum and development of novel preventive and treatment methods
犬新孢子虫入侵机制的蛋白质组学分析及新型预防和治疗方法的开发
- 批准号:
18380180 - 财政年份:2006
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$ 12.67万 - 项目类别:
Grant-in-Aid for Scientific Research (B)
イヌのNeospora caninum感染症の臨床的研究
犬新孢子虫感染的临床研究
- 批准号:
17780237 - 财政年份:2005
- 资助金额:
$ 12.67万 - 项目类别:
Grant-in-Aid for Young Scientists (B)
Antibodies and Congenital Neospora Caninum Transmission
抗体与先天性犬新孢子虫传播
- 批准号:
6620484 - 财政年份:2002
- 资助金额:
$ 12.67万 - 项目类别:
Antibodies and Congenital Neospora Caninum Transmission
抗体与先天性犬新孢子虫传播
- 批准号:
6418003 - 财政年份:2002
- 资助金额:
$ 12.67万 - 项目类别:
Antibodies and Congenital Neospora Caninum Transmission
抗体与先天性犬新孢子虫传播
- 批准号:
6680918 - 财政年份:2002
- 资助金额:
$ 12.67万 - 项目类别:
Neospora Caninumを用いた原虫ベクターの開発
利用犬新孢子虫开发原生动物载体
- 批准号:
01J03940 - 财政年份:2001
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$ 12.67万 - 项目类别:
Grant-in-Aid for JSPS Fellows
Study for NTPase from the newly recognized parasitic protozoan Neospora caninum
新发现的寄生原生动物犬新孢子虫 NTPase 的研究
- 批准号:
10670236 - 财政年份:1998
- 资助金额:
$ 12.67万 - 项目类别:
Grant-in-Aid for Scientific Research (C)