Grant-in-Aid for Scientific Research (C) (2)

科学研究补助金 (C) (2)

• 批准号: 08672328
• 负责人: SUZUKI Noriko
• 金额: $ 1.41万
• 依托单位: Showa University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (C)
• 财政年份: 1996
• 资助国家: 日本
• 起止时间: 1996 至 1998
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-08672328/
• 关键词: Cleft Palate; Alveolar cleft; Bone Bridge; Bone graft; Dental implant; Bone biopsy; 3DCT; Post operative function; 術后機能; 3次元CT法

The following research results were obtained :Secondary bone graft for alveolar cleft were performed by using autogenious bone(PCBM) and allograft(demineralized freeze-dried bone from tissue bank). After 1 year follow up both materials were evaluated clinically and radilgraphically and pathologically.As a result, 1. clinically both grafted materials showed excellent healing condition and by occlusal and dental radiographic examination. 2. By observing 3 dimentional CT, cleft area was filled with new bone which came from graft materials. 3. By performing bone biopsy pathologically new bone was formed around allograft and showed ability of the grafted bone to conduct new bone formation and PCBM showed multiple bone formation after l year.From these results it is confirmed that both materials are useful as graft material for the alveolar cleft.

研究结果如下：牙槽裂二期植骨采用自体骨(PCBM)和同种异体骨(组织库脱钙冻干骨)。经过1年的随访，对两种材料进行了临床、放射学和病理学评价，结果表明：1.临床上两种材料均表现出良好的愈合状况，咬合和牙位X线片检查均显示良好。2.三维CT扫描显示，缺损区充填了植骨材料形成的新骨。3.病理组织学检查显示同种异体骨周围有新骨形成，显示出异体骨具有引导新骨形成的能力，L植入后PCBM呈多发性成骨，证实两种材料均可作为牙槽突裂的移植材料。