Grant-in-Aid for Scientific Research (C) (2)

研究结果如下：采用自体骨（PCBM）和同种异体骨（来自组织库的脱矿冻干骨）进行牙槽骨裂的二次骨移植。经过1年的随访，对两种材料进行了临床、影像学和病理学评估。因此，1。临床结果表明，两种材料均表现出良好的愈合状况。2. 通过三维CT观察，骨裂区被移植材料的新骨填充。3. 病理活检发现同种异体骨周围形成新骨，显示移植骨具有新生骨形成能力，PCBM术后1年出现多发骨形成。结果表明，两种材料均可作为牙槽骨裂的移植材料。

The following research results were obtained :Secondary bone graft for alveolar cleft were performed by using autogenious bone(PCBM) and allograft(demineralized freeze-dried bone from tissue bank). After 1 year follow up both materials were evaluated clinically and radilgraphically and pathologically.As a result, 1. clinically both grafted materials showed excellent healing condition and by occlusal and dental radiographic examination. 2. By observing 3 dimentional CT, cleft area was filled with new bone which came from graft materials. 3. By performing bone biopsy pathologically new bone was formed around allograft and showed ability of the grafted bone to conduct new bone formation and PCBM showed multiple bone formation after l year.From these results it is confirmed that both materials are useful as graft material for the alveolar cleft.