A new progress of physical therapy for the purpose of prevention of cerebrovascular and infeetious diseases

物理治疗预防脑血管及传染病的新进展

• 批准号: 12832011
• 负责人: KUBOTA Kazuo
• 金额: $ 2.5万
• 依托单位: Gunma University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (C)
• 财政年份: 2000
• 资助国家: 日本
• 起止时间: 2000 至 2001
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-12832011/
• 关键词: rehabilitation; cerebrovascular disease; physical therapy; chronic obstructive pulmonary disease; breathing exercise; suppressor; inducer T cell; helper; inducer T ceil; immune function; 凝固・線溶系; 温浴; tPA; PAI-I; 血小板の活性化

We investigated the change in immune function during rehabilitative physical therapy in patients with cerebrovascular and chronic obstructive pulmonary diseases.The effect of a 2-month period of physical therapy on immune function was examined in 11 patients with cerebrovascular disease. Compared with the similar patients who did not receive physical therapy, the ratio of CD4/CD8 cells, response of lymphocytes to mitogens suppressor/inducer T cells, and helper/inducer T cells were increased significantly. Although antibody-dependent cellular cytotoxicity and interleukin-2 receptor were also increased significantly, natural killer cell activity and serum levels of interleukin-2 and inerleukin-6 were not changedThe effect of a 2-month period of physical therapy using breathing pxercise in a pool on immune function was examined in 10 patients with chronic obstructive pulmonary disease. Compared with the similar patients who did not receive physical therapy, CD4-positive cells, the ratio of CD4/CD8 cells, and response of lymphocytes to mitogens were increased significantly. However, serum levels of immunoglobulin were not changed.These findings suggest that physical therapy may increase the immune function in patients with cerebrovascular and chronic obstructive pulmonary diseases.

为探讨脑血管病和慢性阻塞性肺疾病患者在康复理疗过程中免疫功能的变化，对11例脑血管病患者进行为期2个月的康复理疗。与未接受物理治疗的同类患者相比，CD 4/CD 8细胞比值、淋巴细胞对丝裂原抑制/诱导T细胞和辅助/诱导T细胞的反应性均显著升高。10例慢性阻塞性肺疾病患者进行了为期2个月的游泳池内呼吸锻炼的物理治疗，观察了其对免疫功能的影响。与未接受物理治疗的类似患者相比，CD 4阳性细胞、CD 4/CD 8细胞比值和淋巴细胞对有丝分裂原的反应性显著升高。结果提示，运动疗法可提高脑血管病和慢性阻塞性肺疾病患者的免疫功能。

项目成果

Kurabayashi H.: "The effects of hydraulic pressure on atrial natriuvetic peptide during rehabilitative head-out water immersion"Life Sciences. 69. 1017-1021 (2001)

Kurabayashi H.：“康复性头出水浸过程中液压对心房钠肽的影响”生命科学。

Kurabayashi H, et al: "The effects of hydraulic pressure on atrial natriuretic peptide during rehabilitative head-out water immersion"Life Sci. 69. 1017-1021 (2001)

Kurabayashi H 等人：“康复性头出水浸过程中液压对心房钠尿肽的影响”Life Sci。

Kurabayashi H: "The effects of hydraulic pressure on atrial natriuretic peptide during rehabilitative head-out water immersion"Life Sciences. 69. 1017-1021 (2001)

Kurabayashi H：“康复头出水浸过程中液压对心房钠尿肽的影响”生命科学。

倉林 均: "温泉地における旅行者の急性疾患発症とeconomy class syndrome"日本温泉気候物理医学会雑誌. 64. 164-165 (2001)

Hitoshi Kurabayashi：“温泉地区旅行者的急性疾病发作和经济舱综合症”日本温泉气候和物理医学学会杂志 64. 164-165 (2001)。

Kurabayashi H, et al: "Analysis of the circumferences of chest, abdomen, thigh and calf during head-out water immersion"J Jpn Assoc Phys Med Balneol Climatol. 64. 199-202 (2001)

Kurabayashi H 等人：“头部浸水时胸部、腹部、大腿和小腿周长的分析”J Jpn Assoc Phys Med Balneol Climatol。