A study for the diagnosis of inflammatory diseases of joint and spine using FDG-PET; prospective and retrospective studies

FDG-PET诊断关节和脊柱炎症性疾病的研究

• 批准号: 22591362
• 负责人: KUBOTA Kazuo
• 金额: $ 2.58万
• 依托单位: Research Institute, International Medical Center of Japan
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (C)
• 财政年份: 2010
• 资助国家: 日本
• 起止时间: 2010 至 2012
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-22591362/
• 关键词: 核医学(PET を含む); FDG-PET; 炎症性疾患; 関節炎・腱付着部炎; リウマチ性関節炎; 強直性脊椎炎; リウマチ性多発筋痛症; 加齢変化; 核医学診断

We have studied FDG-PET/CT finding of inflammatory diseases of joint and spine. Normal aging effects on the FDG uptake by joints were found to be as minimum as not interfering the diagnosis of disease joints. Polymyalgia rheumatic (PMR) has showed increased FDG uptake in ischial tuberosities, greater trochanters, and lumbar spinous processes characteristically. For the differential diagnosis of seronegative spondyloarthritis (SpA) from PMR, FDG uptake by sacroiliac joints was important.

我们研究了关节和脊柱炎性疾病的FDG-PET/CT表现。研究发现，正常衰老对关节FDG吸收的影响最小，不会干扰疾病关节的诊断。风湿性多肌痛（PMR）表现出坐骨结节、大转子和腰椎棘突的特征性FDG摄取增加。对于血清阴性脊柱关节炎（SpA）与PMR的鉴别诊断，骶髂关节的FDG摄取是重要的。

项目成果

Similarities and differences in FDG-PET/CT findings in spodyloarthropathy, polymyalgia rheumatic and rheumatoid arthritis.

关节软骨病、风湿性多肌痛和类风湿性关节炎 FDG-PET/CT 结果的异同。

• 发表时间: 2013
• 期刊: Joint Bone Sine
• 作者: Yamashita H;Kubota K;et al
• 通讯作者: et al

Inflammation surrounding the vertebralspinous processes as spondylarthritis in Behcet's disease.

白塞氏病中椎棘突周围的炎症，如脊柱关节炎。

• DOI: 10.1007/s10165-012-0713-y
• 发表时间: 2012
• 期刊: Modern Rheumatology
• 影响因子: 2.2
• 作者: Yamashita H;Kubota K;et al
• 通讯作者: et al

PETはもっと役に立つ!新しい使い方と展望

PET的新用途和前景更加有用！

• 发表时间: 2011
• 作者: H. Nishiofuku;S. Matsushima;Y. Inaba;H;Yamaura;Y. Sato;Y. Morishima;K. Kichikawa.;伊藤健吾,加藤隆司;窪田和雄
• 通讯作者: 窪田和雄

18F-FDG-PET/CT で同定されたリウマチ性多発筋痛症における腱付着部炎の重要性

18F-FDG-PET/CT 识别风湿性多肌痛中附着点炎的重要性

• 发表时间: 2011
• 作者: 山下裕之;窪田和雄;高橋裕子;金子礼志;三森明夫
• 通讯作者: 三森明夫

Clinical impact of 18F-FDG PET/CT on the management and diagnosis of infectious spondylitis

• DOI: 10.1097/mnm.0b013e32833bb25d
• 发表时间: 2010-08-01
• 期刊: NUCLEAR MEDICINE COMMUNICATIONS
• 影响因子: 1.5
• 作者: Ito, Kimiteru;Kubota, Kazuo;Mimori, Akio
• 通讯作者: Mimori, Akio