Development of high-dose-rate quasi-x-ray laser generators and applications to medical radiographies including polycapillary radiography

高剂量率准 X 射线激光发生器的开发及其在医学放射成像（包括多毛细管放射成像）中的应用

• 批准号: 12670902
• 负责人: SATO Eiichi
• 金额: $ 2.18万
• 依托单位: IWATE MEDICAL UNIVERSITY
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (C)
• 财政年份: 2000
• 资助国家: 日本
• 起止时间: 2000 至 2002
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-12670902/
• 关键词: quasi-x-ray laser; quasi-monochromatic x-ray; plasma x-ray source; characteristic x-ray amplification; characteristic x-ray; polycapillary plate; x-ray lens; high signal to noise ratio; ポリキャピラリー; 平行X線ビーム; コヒーレンス; 擬似単色X線; フィルムレスCRシステム

Quasi-x-ray laser generator : The high-voltage main condenser is charged up to 55 kV by a power supply, and electric charges in the condenser are discharged to the tube after triggering the cathode electrode with the trigger device. The plasma flash x-rays such as laser are then produced. The x-ray tube is a demountable cold cathode triode that is connected to the turbo molecular pump with a pressure of approximately 1 mPa, and the target elements are iron, nickel, copper, molybdenum, silver, and cerium.Measurement of x-ray spectra from weakly ionized plasma : X-ray spectra from the plasma source were measured by a transmission-type spectrometer with a lithium fluoride curved crystal of 0.5 mm in thickness. The spectra were taken by a computed radiography (CR) system with a wide dynamic range, and relative x-ray intensity was calculated from Dicom digital data. In fact, we observed quite sharp lines of K-series characteristic x-rays such as lasers, while bremsstrahlung rays were hardly … More detected.Divergence by lead slits : In order to measure the difference in characteristics between x-rays from a conventional tube and these from the plasma tubes, we employed two lead slits in order to measure the divergence of the x-rays. As compared with x-rays from a conventional tube with a tungsten target, the characteristic x-rays from linear plasmas of copper and molybdenum were diffused greatly after passing through the two slits.High contrast angiography using a cerium target x-ray tube : Characteristic x-rays from a cerium target are useful to perform angiography using an iodine-based contrast medium, since the photon energies of K-series lines of cerium are slightly higher than the energy of the K-absorption edge of iodine. In angiography of a larger heart extracted from a dog, using iodine spheres, the coronary arteries were clearly visiblePolycapillary radiography : Using a plane-focus plasma x-ray tube in conjunction with a polycapillary plate, we performed quasi-monochromatic parallel radiography achieved with the CR system. Less

准X射线激光发生器：高压主电容器由电源充电至55 kV，用触发装置触发阴极电极后，电容器中的电荷向管内放电。然后产生等离子闪光X射线，例如激光。 X射线管是可拆卸的冷阴极三极管，连接到压力约为1 mPa的涡轮分子泵，目标元素是铁、镍、铜、钼、银和铈。弱电离等离子体的X射线光谱的测量：通过带有氟化锂的透射型光谱仪测量来自等离子体源的X射线光谱 厚度为 0.5 毫米的弧形水晶。光谱由具有宽动态范围的计算机放射线照相 (CR) 系统拍摄，并根据 Dicom 数字数据计算相对 X 射线强度。事实上，我们观察到K系列特征X射线（例如激光）的线非常清晰，而轫致辐射几乎检测不到。铅狭缝的发散：为了测量传统管的X射线与等离子管的X射线之间的特性差异，我们采用了两个铅狭缝来测量X射线的发散度。与带有钨靶的传统管发出的 X 射线相比，来自铜和钼的线性等离子体的特征 X 射线在通过两个狭缝后发生了很大的扩散。 使用铈靶 X 射线管进行高对比度血管造影：来自铈靶的特征 X 射线对于使用碘基造影剂进行血管造影非常有用，因为铈的 K 系列线的光子能量略低。 高于碘 K 吸收边的能量。在使用碘球对从狗身上摘出的较大心脏进行血管造影时，冠状动脉清晰可见。 多毛细血管射线照相：使用平面聚焦等离子 X 射线管与多毛细血管板结合使用，我们进行了 CR 系统实现的准单色平行射线照相。较少的

项目成果

M.Sagae, E.Sato, T.Usuki, K.Sato, H.Ojima, K.Takayama and Y.Tamakawa: "Tentative study on flash ultraviolet generator for high-speed microscopy"SPIE. 4183. 405-412 (2000)

M.Sagae、E.Sato、T.Usuki、K.Sato、H.Ojima、K.Takayama 和 Y.Tamakawa：“高速显微镜用闪光紫外线发生器的尝试性研究”SPIE。

E.Sato, M.Komatsu, Y.Hayasi, E.Tanaka, H.Mori, T.Kawai, T.Ichimaru, K.Takayama and H.Ido: "Quasi-monochromatic parallel radiography achieved with a polycapillary"Proc. Of 3^<rd> Korea-Japan Joint Meeting on Medical Physics. 418-421 (2002)

E.Sato、M.Komatsu、Y.Hayasi、E.Tanaka、H.Mori、T.Kawai、T.Ichimaru、K.Takayama 和 H.Ido：“用多毛细管实现准单色平行射线照相”Proc。

M.Komatsu, E.Sato, Yhayasi, T.Usuki, K.Sato, H.Ojima. K.Takayama and H.Ido: "Low-photon energy plasma flash x-ray generator (LPFXG-2002)"SPIE. in press. (2002)

M.Komatsu、E.Sato、Yhayasi、T.Usuki、K.Sato、H.Ojima。

M.Sagae, E.Sato, M.Komatsu, Y.Hayasi, T.Usuki, K.Sato, H.Ojima, K.Takayama and H.Ido: "High-intensity flash light generator and its application"SPIE. in press. (2002)

M.Sagae、E.Sato、M.Komatsu、Y.Hayasi、T.Usuki、K.Sato、H.Ojima、K.Takayama 和 H.Ido：“高强度闪光发生器及其应用”SPIE。

E.Sato, et al.: "Characteristics of the low photon energy plasma x-ray generator"SPIE. 4508. 193-201 (2001)

E.Sato 等人：“低光子能量等离子体 X 射线发生器的特性”SPIE。