No Invasive Methods For Cell Proliferation Activity Using Superconduction Quantum Interference Device

2001年，我们尝试用超导量子干涉仪测量电磁场随细胞增殖的变化。由于空气循环系统为细胞增殖保持最佳温度，使测试条件变差，大量噪声和基线移位对微电磁场变化的检测产生干扰。因此，为了检测微电磁场随细胞增殖的变化，我们花了很长时间才获得了良好的条件。然而，我们无法得到该测试系统的最优条件。明年我们尝试在室温下测量电磁场随细胞增殖的变化。减小了噪声和基线偏移。然而，我们没有发现明显的变化。不幸的是，我们的研究无法使用SQUID的单通道香炉，于是我们申请使用多通道香炉进行脑活动。现在我们将尝试在不久的将来为我们的研究校准电磁场，我们还将继续研究骨组织在愈伤组织形成过程中的阻抗，以检测组织水平的活动。我们使用家兔胫骨长骨痂。等待期为1周，延长率为0.5mm，每日2次。随着愈伤组织的成熟，延长组织的阻抗值逐渐增加。阻抗为5.41 ^^+__- 1.75 KΩ。为正常骨痂阻抗与恶性骨肿瘤组织的比较提供了有用的数据

We tried to measure a electoromagnetic field changes with cell proliferation using Superconduction Quantum Interference Device in 2001. A lot of noise and base line shift made disturbance of detection of the micro electromagnetic field changes, becouse air circulating system to keep optimal temperature for cell proliferation made the test condition worse. Therefore, we took a long time to get the good condition in order to detect the micro electoromagnetic field changes with cell proliferation. However, we could not get the optimal conditions for this test system. Next year we tried to measure the electlomagnetic field changes with cell proliferation under room temperature. The noise and base line shift was reduced. However, we could not detect remarkable changes. Unfortunately, mono channel censer of SQUID could not be available to our research, then we applied to use the multi channel censers for brain activity. Now we will try to calibrate the electromagnetic fields for our study in near futureWe also continued to research for the impedance of bone tissue in the process of callus formation in order to detect tissue level activity. We used lengthend callus of tibiae in rabbits. The waiting period was 1 week and the lengthening rate was 0.5mm twice daily. The impedance values of lengthened tissue increased with the callus maturation. Impedance was 5.41 ^^+__- 1.75 KΩ. It was useful data as normal callus impedance in order to compare to malignant bone tumor tissue