Instrument capable of grading eyes with severe visual loss: Estimation of visual function utilizing a novel device called the Low Vision Evaluator

能够对严重视力丧失的眼睛进行分级的仪器：利用称为低视力评估器的新型设备评估视觉功能

• 批准号: 13671815
• 负责人: NAKAGAWA Yoichi
• 金额: $ 2.3万
• 依托单位: Tohoku University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (C)
• 财政年份: 2001
• 资助国家: 日本
• 起止时间: 2001 至 2002
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-13671815/
• 关键词: Low vision; Visual function; Retinitis pogmentosa; Claucoma; Diabetic retinopathy; 加齢黄斑変性

The purpose of this study is to develop an instrument capable of measuring and quantifying the visual capabilities of patients with severe yisual loss. The LoVE (Low Vision Evaluator) was made up of a pair of goggles with white, light-emitting diode as a stimulus, a control box, an on―off button to signal the detection of a stimulus, and a printer for permanent records. There were 15 levels of stimuli (combination of 5 intensitics and 3durations). The stimuli were delivered in a random sequence with an audio signal. Each eye was tested separately.The LoVE was capable of grading the visual function of retinitis pigmentosa (RP) patients with hand movement (HM) and light perception (LP) vision into finer steps. The Snellen visual acuity and visual field size (Steradian) were significantly correlated with LoVE score in RP patients. There were high correlations between the LoVE score and residual peripheral visual field in glaucoma eyes categorized as Vb Kozaki's classification. The LoVE thresholds of proliferative diabetic retinopathy (PDR) patients, whose fundi could not be observed due to vitreous hemorrhage and whose visual acuity was LP or HM, were determined. The LoVH thresholds of patients with a retinal detachment ware significantly lower than that of patients with no retinal detachment. The correlation between the LoVE thresholds and the amplitude of a- and b-waves of the ERG was significant. The LoVE is capable of grading the visual function of PDR patients with conventional LP and HM vision into finer steps, and it can be used to assess the visual function of patients with vitreous hemorrhage.The testing procedures were simple for the patients and examiner, and this instrument can be used to assess the effectiveness of medical and surgical therapy in patients with severe visual loss.

本研究的目的是开发一种能够测量和量化严重视力丧失患者视觉能力的仪器。Low Vision Evaluator（低视力评估器）由一副带有白色发光二极管作为刺激的护目镜、一个控制盒、一个指示检测到刺激的开关按钮和一台用于永久记录的打印机组成。刺激有15个水平（5个强度和3个持续时间的组合）。刺激以随机顺序与音频信号一起传递。每只眼睛分别进行测试。LoVE能够对具有手部运动（HM）和光感知（LP）视觉的色素性视网膜炎（RP）患者的视觉功能进行更精细的分级。RP患者的Snellen视敏度和视野大小（Steradian）与LoVE评分有显著相关。按Vb Kozaki分级的青光眼，LoVE评分与剩余周边视野高度相关。测定增生性糖尿病视网膜病变（PDR）患者因玻璃体出血无法观察眼底，视力为LP或HM的LoVE阈值。视网膜脱离患者的LoVH阈值明显低于无视网膜脱离患者。LoVE阈值与ERG a波和b波振幅的相关性显著。LoVE能够对常规LP和HM视力的PDR患者的视觉功能进行更精细的分级，并可用于玻璃体出血患者的视觉功能评估。该仪器对患者和检查人员操作简便，可用于评估严重视力丧失患者的内科和外科治疗效果。

项目成果

中川陽一, 板橋俊隆, 和田裕子, 佐藤肇, 川村后幸, 吉岡由貴, 舘花裕子, 玉井信: "時間固定型Low Vision Evaluator(LoVE)による網膜色素変性患者の視機能評価"厚生省特定疾患網膜脈絡膜・視神経萎縮症調査研究班平成12年度研究報告書. 243-246 (2001)

Yoichi Nakakawa、Toshitaka Itabashi、Yuko Wada、Hajime Sato、Gouyuki Kawamura、Yuki Yoshioka、Yuko Tatehana、Makoto Tamai：“使用固定时间低视力评估器（LoVE）评估色素性视网膜炎患者的视觉功能”厚生省指定疾病视网膜脉络膜和视神经萎缩调查研究小组 2000 年研究报告 243-246 (2001)。

秋山博, 中川陽一, 高橋佳奈, 和田裕子, 玉井信: "Low Vision Evaluator(LoVE)による周辺部残存視野の評価"臨床眼科. 56・8. 1377-1381 (2002)

Hiroshi Akiyama、Yoichi Nakakawa、Kana Takahashi、Yuko Wada、Makoto Tamai：“使用低视力评估器（LoVE）评估周边残余视野”临床眼科 56・8。

國方彦志, 中川 陽一, 角田雅宏, 玉井信: "重度低視力者の視機能評価とその測定機器Low Vision Evaluatorの開発"日本眼科学会雑誌. 105・3. 161-166 (2001)

Hikoshi Kunikata、Yoichi Nakakawa、Masahiro Tsunoda、Makoto Tamai：“严重低视力患者的视觉功能评估和测量设备、低视力评估器的开发”，日本眼科学会杂志 105・3。 (2001)

川村后幸, 和田裕子, 板橋俊隆, 中川陽一, 玉井信: "網膜色素変性の患者における日常生活の難易度とLow Vision Evaluator(LoVE)スコアの関係"厚生省特定疾患 網膜脈絡膜・視神経萎縮症調査研究班平成12年度研究報告書. 232-234 (2001)

Houyuki Kawamura、Yuko Wada、Toshitaka Itabashi、Yoichi Nakakawa、Makoto Tamai：“视网膜色素变性患者的日常生活难度与低视力评估器（LoVE）评分之间的关​​系”厚生省指定疾病视网膜脉络膜和视神经萎缩研究研究小组研究报告 2000. 232-234 (2001)

Itabashi T, Nakagawa Y, et al.: "Assessmeni of Helcnienc for Retinitis Pigmentosa Using Low Vision Evalualor (LoVE)"Annual report of the Chorioretinal / Optic Atrophy Research Committee, the Ministry of Health, Labor and Welfare of Japan. 239-42 (2001)

Itabashi T、Nakakawa Y 等人：“Helcnienc 使用低视力评估器 (LoVE) 评估视网膜色素变性”日本厚生劳动省脉络膜视网膜/视神经萎缩研究委员会的年度报告。