personalized medicine of implants based on biomechanics simulation

本研究的目的是开发个体化种植体治疗，以阐明旋入扭矩和骨质之间的相关性，确定上部结构的设计，并评估随时间推移种植体周围骨结构的定量观察。这项研究表明，显着的正相关性之间的旋入扭矩的骨量和弹性模量的评价，通过口内X线片和这种评价技术可以用来简单和定量地预测种植体植入前的初期稳定性。此外，在上部结构设计方面，观察了尖点角，明确了桥台产生的张拉力。因此，实现了考虑每个个体的生物力学的上部结构的制造。接下来，我们通过检查口内X线片的结构参数来评估种植体周围骨结构的连续变化的可能性。这项研究表明，种植体周围骨结构的变化可以通过监测口内X线片记录的骨小梁结构参数的变化来评估。如果明确了种植体上过度载荷引起的骨小梁结构参数的变化，则可以通过监测这些变化来预测骨结合的丧失，从而提供更可预测的种植体治疗。

The purpose of this study was to develop the individual implant treatment to clarify the correlation between insertion torque and bone quality and determine design of the superstructure and assess quantitive observation of peri-implant bone stracture with time. This study suggests that significant positive correlation were found between insertion torque for bone mass and elastic modulus as evaluated by intraoral radiographs and this evaluation technique may be used to simply and quantitatively to anticipate implant primary stability prior to implant placement. Moreover regarding design of the superstructure, the cusp angle is observed, tensible force produced in abutment was able to be clarified. Thereby, manufacture of the superstructure in consideration of the biomechanics of each individual was attained. To the next we test the possibility of evaluating serial change in peri-implant bone structures by examining structural parameters in intraoral radiographs. This study suggest that changes in peri-implant bone structure can be evaluated at intervals by monitoring the changes in structural parameter of trabecular bone as recorded in intraoral radiographs. If changes in structural parameters of the trabecular bone caused by excessive loading on implants are clarified, loss of osseointegration may be anticipated by monitoring the changes providing more predictable implant treatment.