Development of a new tissue conditioner possessed of an antibacterial/-fungal effect

第一项研究的目的是阐明五种市售的含银沸石（2wt%）的组织调理剂对白色念珠菌和院内呼吸道感染致病菌金黄色葡萄球菌和铜绿假单胞菌的体外抗菌作用。含银沸石的组织调理剂在体外对唾液中的白色念珠菌和医院内呼吸道感染致病菌具有4周的抗菌作用，第二项研究的目的是使用非共振强迫振动法评估含银沸石（0.2.5wt%和10wt%）的相同五种组织调理剂的动态粘弹性。在37 ° C下，在没有和有浸泡在蒸馏水和人工唾液中24小时、1周和4周后进行测量。结果表明，组织调理剂的动态粘弹性能受贮存条件和贮存时间的影响较大，而银沸石的影响较小。

The purpose of the first study was to elucidate the in vitro antimicrobial effect of five commercially available tissue conditioners containing silverzeolite (2 wt%) on Candida albicans and nosocomial respiratory infectioncausing bacteria, Staphylococcus aureus and Pseudomonas aeruginosa. Tissue conditioners containing silver-zeolite have been shown to have antimicrobial effects for 4 weeks on C.albicans and nosocomial respiratory infection-causing bacteria in saliva in vitro.The purpose of the second study was to evaluate dynamic viscoelastic properties of same five tissue conditioners containing silver-zeolite (0.2.5 and 10 wt%) using non-resonance forced vibration method. Measurements were carried out after without and with immersion in distillled water and artificial saliva at 37ﾟC for 24 hours, 1 week and 4 weeks. The results indicate that dynamic viscoelastic properties of tissue conditioners are influenced considerably by storage conditions and the time proceeds, and that there is a small effect of silver-zeolite.