Centrifugal type artificial heart of high durability using a magnetic bearing

使用磁力轴承的高耐久性离心式人工心脏

• 批准号: 17360070
• 负责人: SHINSHI Tadahiko
• 金额: $ 9.73万
• 依托单位: Tokyo Institute of Technology
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (B)
• 财政年份: 2005
• 资助国家: 日本
• 起止时间: 2005 至 2006
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-17360070/
• 关键词: Artificial Heart; Centrifugal Pump; Magnetic Bearing; Hemolysis; Blood Pump

Implantable ventricular assist devises and disposable blood pumps have been developed for heart disease patients.1)Implantable ventricular assist deviseA magnetically levitated (maglev) centrifugal blood pump (CBP), intended for use as a ventricular assist device, needs to be highly durable and reliable for long term use without any mechanical failure. Furthermore, maglev CBPs should be small enough to be implanted into patients of various size and weight. We have developed a compact maglev CBP employing a two-degree-of-freedom controlled magnetic bearing, with a magnetically suspended impeller directly driven by an internal brushless direct current (DC) motor. The magnetic bearing actively controls the radial motion of the impeller and passively supports axial and angular motions using a permanent magnet embedded in the impeller. The overall dimensions of the maglev CBP are 65 mm in diameter and 40 mm in height. The total power consumption and pump efficiency for pumping 6 L/min again … More st a head pressure of 105 mm Hg were 6.5 W and 21%, respectively. The hemolytic characteristics of the maglev CBP were compared with those of the Medtronic Biomedicus BPX-80, which demonstrated the superiority of the maglev CBP.2)Disposable blood pumpA magnetically levitated (MagLev) centrifugal blood pump (MedTech Dispo) has been developed for a disposable extracorporeal system. The pump design is aimed at eliminating mechanical contact of an impeller, realization of a simple disposable mechanism, and reduction of the heating effect on blood due to a motor and a magnetic bearing. The disposable pump head with priming volume of 23 mL consists of top and bottom housings, the impeller and the rotor with diameter of 50 mm. The pump can provide more than 300 mmHg against 5 L/min. Normalized index of hemolysis (NIH) of the MedTech Dispo is 0.0025 ± 0.0005 g/100L at 5 L/min against 250 mmHg. This is one seventh of that of Bio Pump BPX-80 (Medtronic Inc, U.S.A.) of 0.0170 ± 0.0096 g/100L. These results show that the MedTech Dispo realizes high pump performance and low blood trauma. Less

为心脏病患者开发了可植入的心室辅助设计和一次性血泵。1）可植入的心室辅助磁性磁性（MAGLEV）离心血泵（CBP），旨在用作心室辅助装置，需要长期使用任何机械故障，可用于长期使用。此外，岩浆CBP应该足够小，以植入各种大小和体重的患者中。我们已经开发了一种紧凑的磁岩CBP，该磁磁性磁轴承使用了两度的磁性磁性轴承，并直接由内部无刷直流电流（DC）电动机直接驱动磁悬浮的叶轮。磁性轴承积极控制叶轮的径向运动，并使用嵌入叶轮中的永久磁铁被动地支撑轴向和角运动。岩浆CBP的总体尺寸为直径65毫米，高度为40毫米。再次泵送6 L/min的总功耗和泵效率……更多的头压为105毫米Hg，分别为6.5 W和21％。将Maglev CBP的溶血性特性与Medtronic Biomedicus BPX-80的溶血特性进行了比较，这些杂志BPX-80证明了Maglev CBP.2）可支配的血液Pumpa磁性磁线（Maglev）中心血液泵（Medtech）已开发出来，已开发出来用于销售额外的系统。泵设计旨在消除叶轮的机械接触，简单的一次性机制的实现以及减少由于电动机和磁性轴承而引起的对血液的加热效应。启动量为23 mL的一次性泵头由顶部和底部壳体组成，叶轮和直径为50 mm的转子组成。该泵可提供超过300 mmHg的泵，而5 l/min。 MEDTECH DISPO的溶血指数（NIH）为0.0025±0.0005 g/100L，在5 l/min的情况下为250 mmHg。这是0.0170±0.0096 g/100L的生物泵BPX-80（Medtronic Inc.）的第七个。这些结果表明，MEDTECH DISPO实现了高泵性能和低血外伤。较少的

项目成果

Feasibility of a Miniature Centrifugal Rotary Blood Pumps for Low-Flow Circulation in Children and Infants

微型离心旋转血泵用于儿童和婴儿低流量循环的可行性

• 发表时间: 2005
• 期刊: ASAIO Journal 2005
• 作者: S.Takatani;H.Hoshi;K.Tajima;K.Ohuchi;M.Nakamura;J.Asama;T.Shinshi;M.Yoshikawa
• 通讯作者: M.Yoshikawa

Disposable, Maglev Centrifugal Blood Pump : Design and In Vitro Performance

一次性磁悬浮离心血泵：设计和体外性能

• 发表时间: 2005
• 期刊: Artificial Organs 29,7
• 作者: H.Hoshi;J.Asama;T.Shinshi;K.Ohuchi;T.Mizuno;H.Arai;A.Shimokohbe;S.Takatani
• 通讯作者: S.Takatani

Detection of left ventricular function from the Mag-Lev impeller behavior

从 Mag-Lev 叶轮行为检测左心室功能

• 发表时间: 2006
• 期刊: Artificial Organs 30,5
• 作者: Hideo Hoshi;Junichi Asama;Chikara Hara;Wataru Hijikata;Tadahiko Shinshi;Akira Shimokohbe;Setsuo Takatani
• 通讯作者: Setsuo Takatani

マイクロ磁気軸受モータの研究

微型磁轴承电机的研究

• 发表时间: 2006
• 期刊: 精密工学会誌 72,5
• 作者: 黒木次郎;進士忠彦;李 黎川;下河辺明
• 通讯作者: 下河辺明

使い捨て磁気浮上式血液ポンプ

一次性磁悬浮血泵

• 发表时间: 2005