Centrifugal type artificial heart of high durability using a magnetic bearing

使用磁力轴承的高耐久性离心式人工心脏

• 批准号: 17360070
• 负责人: SHINSHI Tadahiko
• 金额: $ 9.73万
• 依托单位: Tokyo Institute of Technology
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (B)
• 财政年份: 2005
• 资助国家: 日本
• 起止时间: 2005 至 2006
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-17360070/
• 关键词: Artificial Heart; Centrifugal Pump; Magnetic Bearing; Hemolysis; Blood Pump

Implantable ventricular assist devises and disposable blood pumps have been developed for heart disease patients.1)Implantable ventricular assist deviseA magnetically levitated (maglev) centrifugal blood pump (CBP), intended for use as a ventricular assist device, needs to be highly durable and reliable for long term use without any mechanical failure. Furthermore, maglev CBPs should be small enough to be implanted into patients of various size and weight. We have developed a compact maglev CBP employing a two-degree-of-freedom controlled magnetic bearing, with a magnetically suspended impeller directly driven by an internal brushless direct current (DC) motor. The magnetic bearing actively controls the radial motion of the impeller and passively supports axial and angular motions using a permanent magnet embedded in the impeller. The overall dimensions of the maglev CBP are 65 mm in diameter and 40 mm in height. The total power consumption and pump efficiency for pumping 6 L/min again … More st a head pressure of 105 mm Hg were 6.5 W and 21%, respectively. The hemolytic characteristics of the maglev CBP were compared with those of the Medtronic Biomedicus BPX-80, which demonstrated the superiority of the maglev CBP.2)Disposable blood pumpA magnetically levitated (MagLev) centrifugal blood pump (MedTech Dispo) has been developed for a disposable extracorporeal system. The pump design is aimed at eliminating mechanical contact of an impeller, realization of a simple disposable mechanism, and reduction of the heating effect on blood due to a motor and a magnetic bearing. The disposable pump head with priming volume of 23 mL consists of top and bottom housings, the impeller and the rotor with diameter of 50 mm. The pump can provide more than 300 mmHg against 5 L/min. Normalized index of hemolysis (NIH) of the MedTech Dispo is 0.0025 ± 0.0005 g/100L at 5 L/min against 250 mmHg. This is one seventh of that of Bio Pump BPX-80 (Medtronic Inc, U.S.A.) of 0.0170 ± 0.0096 g/100L. These results show that the MedTech Dispo realizes high pump performance and low blood trauma. Less

植入式心室辅助装置和一次性血泵已被开发用于心脏病患者。1）植入式心室辅助装置磁悬浮（Maglev）离心血泵（CBP），预期用作心室辅助装置，需要高度耐用和可靠，以长期使用而没有任何机械故障。此外，磁悬浮CBP应该足够小，以植入各种体型和体重的患者体内。我们已经开发了一种紧凑的磁悬浮CBP采用两个自由度的控制磁轴承，与磁悬浮叶轮直接由内部无刷直流（DC）电机驱动。磁力轴承主动控制叶轮的径向运动，并使用嵌入叶轮中的永磁体被动地支持轴向和角向运动。磁悬浮CBP的总尺寸为直径65毫米，高40毫米。再次泵送6 L/min的总功耗和泵效率 ...更多信息 105 mm Hg的起始压力分别为6.5 W和21%。将磁悬浮CBP的溶血特性与Medtronic Biomedicus BPX-80的溶血特性进行了比较，证明了磁悬浮CBP的优越性。2）一次性血泵磁悬浮（MagLev）离心血泵（MedTech Dispo）已开发用于一次性体外系统。该泵的设计旨在消除叶轮的机械接触，实现简单的一次性机构，并减少由于电机和磁轴承对血液的加热效应。预充容量为23 mL的一次性使用泵头由上下外壳、叶轮和直径为50 mm的转子组成，泵在5 L/min时可提供300 mmHg以上的压力，MedTech Dispo在5 L/min时对250 mmHg的标准化溶血指数（NIH）为0.0025 ± 0.0005 g/100 L。这是Bio Pump BPX-80（Medtronic Inc，U.S.A.）的七分之一。0.0170 ± 0.0096 g/100 L。这些结果表明，MedTech Dispo实现了高泵性能和低血液损伤。少

项目成果

Detection of left ventricular function from the Mag-Lev impeller behavior

从 Mag-Lev 叶轮行为检测左心室功能

• 发表时间: 2006
• 期刊: Artificial Organs 30,5
• 作者: Hideo Hoshi;Junichi Asama;Chikara Hara;Wataru Hijikata;Tadahiko Shinshi;Akira Shimokohbe;Setsuo Takatani
• 通讯作者: Setsuo Takatani

マイクロ磁気軸受モータの研究

微型磁轴承电机的研究

• 发表时间: 2006
• 期刊: 精密工学会誌 72,5
• 作者: 黒木次郎;進士忠彦;李 黎川;下河辺明
• 通讯作者: 下河辺明

A compact, high-efficiency and low hemolytic centrifugal blood pump with a magnetically levitated impeller

一种紧凑、高效、低溶血的磁悬浮叶轮离心血泵

• 发表时间: 2006
• 期刊: Artificial Organs 30,3
• 作者: J.Asama;T.Shinshi;H.Hoshi;S.Takatani;A.Shimokohbe
• 通讯作者: A.Shimokohbe

使い捨て磁気浮上式血液ポンプ

一次性磁悬浮血泵

• 发表时间: 2005

Computational fluid dynamics (CFD) analysis of the pediatric tiny centrifugal blood pump (TinyPump)

• 发表时间: 2005-09
• 作者: K. Kido;H. Hoshi;N. Watanabe;K. Tajima;H. Kataoka;M. Nakamura;Junnichi Asama;T. Shinshi;M. Yoshikawa;S. Takatani;N. Watanabe