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Investigation on Preventive Effects of Pregnancy Mongolian Large Intake of Dairy Products for Cleft Lip and/or Palate Incidence

蒙古族孕期大量摄入乳制品预防唇腭裂发病效果的调查

基本信息

批准号：
17406028
负责人：
NATSUME Nagato
金额：
$ 4.53万
依托单位：
Aichi Gakuin University
依托单位国家：
日本
项目类别：
Grant-in-Aid for Scientific Research (B)
财政年份：
2005
资助国家：
日本
起止时间：
2005 至 2007
项目状态：
已结题

来源：
https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-17406028/
关键词：
Mongolian Dairy Products Prevention Cleft Lip Cleft Palate 先天異常予防

项目摘要

1. Surveys about the incidence of cleft lip and palate were conducted in Mongolia. We found total 23 patients: 21 in remote prefectures (2 in Arkhangai Prefecture, 1 in Bayan-Ulgii, 4 in Bayankhongor, 1 in Bulgan, 1 in Govi-Altai, 5 in Orkhon, 1 in Umnugovi, 3 in Uvs, 2 in Khovd, and 1 in Khentii), and 2 in Ulaanbaatar Prefecture.2. Effects of dairy products taken before pregnancy on the incidence of cleft lip and palate were studied to examine preventive effects of dairy products. The study was conducted using A/J mice that develop cleft lip and palate easily. The NJ mice were given cheese and CA-1 that is a common mouse-feed for breeding ad libitum 2 weeks before pregnancy and during pregnancy to compare the incidence of cleft lip and palate with control groups of non-cheese. The control groups were given only CA-1 feed. The subject groups were given cheese and CA-1: the first subject groups were given cheese made and sold in Japan and the second subject groups were given cheese made … More in Mongolia. An embryo was taken from a dam with Caesarean operation on the day 18 of pregnancy to examine facial and oral abnormalities with a stereoscopic microscope. The result was that the control groups of 134 living embryos had 11 (8.2%) cleft lip and palate embryos. Of them, 6 (4.5%) was cleft palate and 5 (3.7%) was cleft lip and palate. The first subject groups of 137 living embryos given Japanese cheese had 6 (4.4%) cleft lip and palate embryos. Of them, 2 (1.5%) was cleft palate and 4 (2.9%) was cleft lip and palate. The second subject groups of 83 living embryos given Mongolian cheese had 4 (4.5%) cleft lip and palate embryos. Of them, 0 (0.0%) was cleft palate and 4 (4.5%) was cleft lip and palate. Although there was no significant difference between the control groups and subject groups of either the first or the second, the second groups given Mongolian cheese had no cleft palate case. Further, studies using other samples of Mongolian cheese were conducted with mice in the same way as the above. Less

1.在蒙古开展了关于唇腭裂发病率的调查。我们共发现了23例患者：21例在偏远地区（2例在阿尔汉盖州，1例在巴彦乌勒州，4例在巴彦洪戈尔州，1例在布尔干州，1例在戈维阿尔泰州，5例在鄂尔浑州，1例在乌姆努戈维州，3例在乌斯季州，2例在科布多州，1例在肯特州），2例在乌兰巴托州。研究了孕前食用乳制品对唇腭裂发病率的影响，以检验乳制品的预防作用。这项研究是使用容易发生唇腭裂的A/J小鼠进行的。在怀孕前2周和怀孕期间，随意给予NJ小鼠奶酪和CA-1，CA-1是用于繁殖的常用小鼠饲料，以比较唇腭裂的发生率与非奶酪对照组。对照组仅给予CA-1饲料。研究对象组被给予奶酪和CA-1：第一组被给予在日本生产和销售的奶酪，第二组被给予在日本生产和销售的奶酪。 ...更多信息在蒙古。从妊娠第18天剖腹产的母鼠中取出胚胎，用体视显微镜检查面部和口腔畸形。结果表明，对照组134个活胚中有11个（8.2%）为唇腭裂胚。其中腭裂6例（4.5%），唇腭裂5例（3.7%）。给予日本奶酪的137个活胚胎的第一受试者组有6个（4.4%）唇腭裂胚胎。其中腭裂2例（1.5%），唇腭裂4例（2.9%）。第二个受试组的83个活胚胎给予蒙古奶酪，有4个（4.5%）唇腭裂胚胎。腭裂0例（0.0%），唇腭裂4例（4.5%）。虽然第一组和第二组的对照组和受试者组之间没有显著差异，但给予蒙古奶酪的第二组没有腭裂病例。此外，以与上述相同的方式用小鼠进行了使用蒙古奶酪的其他样品的研究。少

项目成果

期刊论文数量（0）

专著数量（0）

科研奖励数量（0）

会议论文数量（0）

专利数量（0）

Comparison of Lifestyles between Mongolian and Japanese Childdren Aged 9-11 years Using a 15-Item Oral Health Questionnaire

使用 15 项口腔健康调查问卷比较蒙古和日本 9-11 岁儿童的生活方式

DOI：
发表时间：
2005
期刊：
Aichi-Gakuin Dental Science VOL.18
影响因子：
0
作者：
Garidkhuu Ariuntuul;夏目長門他;Nagato Natsume;Oktyabri Dulamsuren
通讯作者：
Oktyabri Dulamsuren

Comparison of Lifestyles between Mongolian and Japanease Childdren Aged 9-11 years Using a 15-Item Oral Health Questionnaire

使用15项口腔健康调查问卷比较蒙古族和日本9-11岁儿童的生活方式

DOI：
发表时间：
2005
期刊：
Aichi-Gakuin Dental Science VOL.18
影响因子：
0
作者：
Garidkhuu Ariuntuul;夏目長門他;Nagato Natsume;Oktyabri Dulamsuren;Norjma Bathcimeg;Nagato NATSUME;Oktyabri Dulamsuren;Norjma Bathcimeg;Oktyabri Dulamsuren
通讯作者：
Oktyabri Dulamsuren

Incidence of Cleft Lip and Palate in Mongolia

蒙古唇裂和腭裂的发病率

DOI：
发表时间：
2006
期刊：
Journal of Japanese Cleft Palate Association 31(3)
影响因子：
0
作者：
Garidkhuu Ariuntuul;Nagato NATSUME
通讯作者：
Nagato NATSUME

Comparison of Lifestyles between Mongolian and Japanese Childdren Aged 12-14 years Using a 20-Item Oral Health Questionnaire

使用 20 项口腔健康调查问卷比较蒙古和日本 12-14 岁儿童的生活方式

DOI：
发表时间：
2005
期刊：
Aichi-Gakuin Dental Science VOL.18
影响因子：
0
作者：
Garidkhuu Ariuntuul;夏目長門他;Nagato Natsume;Oktyabri Dulamsuren;Norjma Bathcimeg
通讯作者：
Norjma Bathcimeg

モンゴルにおける口唇・口蓋裂の有病率

蒙古唇裂和腭裂的患病率