In Silico Search for Drug Target Pathways by Gene Networks
In Silico Search for Drug Target Pathways by Gene Networks
批准号:
18300097
负责人:
MIYANO Satoru
金额:
$11.33万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (B)
财政年份:
2006
资助国家:
日本
项目状态:
已结题
起止时间:
2006 至 2008
中文摘要
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英文摘要
遺伝子ノックダウンや薬剤応答などに基づいた遺伝子発現データから大規模遺伝子ネットワークを推定する方法と統計的解析とシミュレーションによる遺伝子ネットワークの解析方法を用いて, 遺伝子ネットワークに基づく, 創薬ターゲットパスウェイを探索するためのバイオインフォマティクス技術を開発した.この技術を使って, 薬剤Fenofibrate, Gefitinib 並びに漢方薬が影響を与えるパスウェイの解析を実現した.
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Analysis of Gene Networks for Drug Target Discovery and Validation
用于药物靶标发现和验证的基因网络分析
DOI:
--
发表时间:
2006
期刊:
Methods in Molecular Biology 360・1
影响因子:
--
作者:
[S.Imoto, Y.Tamada, C.J.Savoie, S.Miyano]
通讯作者:
S.Miyano
Unraveling dynamic activities of autocrine pathways that control drug-response transcriptome networks
揭示控制药物反应转录组网络的自分泌途径的动态活动
DOI:
--
发表时间:
2009
期刊:
Pacific Symposium on Biocomputing Vol.14
影响因子:
--
作者:
[Y. Tamada, H. Araki, S. Imoto, M. Nagasaki, A. Doi, Y. Nakanishi, Y. Tomiyasu, K. Yasuda, B. Dunmore, D. Sanders, S. Humphries, C. Print, D.S. Charnock-Jones, K. Tashiro, S. Kuhara, S. Miyano]
通讯作者:
S. Miyano
Gene-L'EXPO: a Tool to Extract Knowledge From Transcriptomes and Find 'Literature-Sparse' Relationships Between Genes and Tissues
Gene-LEXPO:从转录组中提取知识并发现基因与组织之间“文献稀疏”关系的工具
DOI:
--
发表时间:
2008
期刊:
Proc. AMIA Annual Symposium 2008
影响因子:
--
作者:
[Hishiki, T., Tamada, I., Okubo, K.]
通讯作者:
K.
DOI:
10.1007/978-1-4939-7717-8
发表时间:
2018
期刊:
JAWRA Journal of the American Water Resources Association
影响因子:
--
作者:
[Dr. Arthur Dong]
通讯作者:
Dr. Arthur Dong
Identification of activated transcription factors from microarray gene expression data of Kampo-medicine treated mice
从汉方药物治疗小鼠的微阵列基因表达数据中鉴定激活的转录因子
DOI:
--
发表时间:
2007
期刊:
Genome Informatics 18
影响因子:
--
作者:
[R. Yamaguchi, et. al.(10名中3番目)]
通讯作者:
et. al.(10名中3番目)
共 18 条
Drug-response pathway analysis methods based on network analysis
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批准号:22300099
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项目类别:Grant-in-Aid for Scientific Research (B)
-
资助金额:$5.57万
-
财政年份:2010
-
负责人:MIYANO Satoru
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依托单位:
Estimation and simulation of gene networks for developing in silico biological networks
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批准号:17017008
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项目类别:Grant-in-Aid for Scientific Research on Priority Areas
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资助金额:$59.84万
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财政年份:2005
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负责人:MIYANO Satoru
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依托单位:
Information Scientific Foundations of Knowledge Discovery from Proteome Data
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批准号:15300099
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$10.56万
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财政年份:2003
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负责人:MIYANO Satoru
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依托单位:
Information Technoloy for Gene Network Analysis
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批准号:15014205
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项目类别:Grant-in-Aid for Scientific Research on Priority Areas
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资助金额:$20.48万
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财政年份:2003
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负责人:MIYANO Satoru
-
依托单位:
Foundations of Computational Knowledge Discovery from cDNA Microarray Data
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批准号:12480080
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$9.22万
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财政年份:2000
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负责人:MIYANO Satoru
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依托单位:
Knowledge Discovery in Databases
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批准号:10143102
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项目类别:Grant-in-Aid for Scientific Research on Priority Areas (A)
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资助金额:$76.67万
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财政年份:1998
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负责人:MIYANO Satoru
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依托单位:
Development of Data Mining System Using Binary Decision Diagrams for Knowledge Representation
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批准号:09558032
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项目类别:Grant-in-Aid for Scientific Research (B)
-
资助金额:$8.19万
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财政年份:1997
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负责人:MIYANO Satoru
-
依托单位:
Development of Parallel Knowledge Acquisition System
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批准号:06558047
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项目类别:Grant-in-Aid for Scientific Research (A)
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资助金额:$11.07万
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财政年份:1994
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负责人:MIYANO Satoru
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依托单位:
STUDY ON EFFICIENT SEARCH ALGORITHMS
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批准号:06680326
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项目类别:Grant-in-Aid for General Scientific Research (C)
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资助金额:$1.41万
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财政年份:1994
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负责人:MIYANO Satoru
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依托单位:
Algorithmic research on computational learning and teaching
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批准号:02680031
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项目类别:Grant-in-Aid for General Scientific Research (C)
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资助金额:$1.15万
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财政年份:1990
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负责人:MIYANO Satoru
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依托单位:
海外基金