课题基金 / 基金详情

Implementation of chemical biology using novel affinity resins

Implementation of chemical biology using novel affinity resins
使用新型亲和树脂实施化学生物学
批准号:
19350086
负责人:
HOSOYA Ken
金额:
$12.48万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (B)
财政年份:
2007
资助国家:
日本
项目状态:
已结题
起止时间:
2007 至 2009

项目摘要

项目成果

HOSOYA Ken的其他基金

相似基金

相关文献

中文摘要
翻译
点击翻译按钮获取中文摘要
英文摘要
I have developed completely new, monolithic affinity resins for researches of target proteins of certain bioactive substances, which have been very important for novel drag discovery. Based on careful studies, I have realized great suppression of non-specific adsorption of proteins based on "soft" surface of affinity resins and really improved capture of the target proteins, which have been never realized using commercially available affinity resins. In addition, using surface modification, environment of the immobilized ligand has been controlled to capture various target proteins in certain environment. These results will contribute implementation of chemical biology.
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
Polymer-based monolithic columns in capillary formant tailored by using controlled in situ polymerization
通过使用受控原位聚合定制的毛细管共振峰中基于聚合物的整体柱
DOI: --
发表时间: 2009
期刊: J.Separation Sci. 32
影响因子: --
作者: [H. Aoki, N. Tanaka, T. Kubo, K. Hosoya]
通讯作者: K. Hosoya
Importance of surface properties of affinity resin for capture of a target protein, Cyclooxygenase-1
亲和树脂表面特性对于捕获目标蛋白 Cyclooxygenase-1 的重要性
DOI: --
发表时间: 2009
期刊: Bioorganic and Medicinal Chemistry 17
影响因子: --
作者: [T. Mori, T. Kubo, K. Kaya, and K. Hosoya]
通讯作者: and K. Hosoya
A novel chip device based on wired capillary packed with high performance polymer-based monolith for HPLC:
一种基于有线毛细管的新型芯片装置,填充有高性能聚合物基整料,用于 HPLC:
DOI: --
发表时间: 2008
期刊: Anal. Sci. 24(1)
影响因子: --
作者: [K. Hosoya, et. al.]
通讯作者: et. al.
Novel polymer monolithic column for hydrophilic compounds
用于亲水化合物的新型聚合物整体柱
DOI: --
发表时间: 2009
期刊: Chromatographia 70
影响因子: --
作者: [T. Kubo, F. Watanabe, N. Kimura, K. Kaya, K. Hosoya]
通讯作者: K. Hosoya
21
    Development of Biocompatible Co-continuous Membrane for Immune Depression
    • 批准号:
      23655149
    • 项目类别:
      Grant-in-Aid for Challenging Exploratory Research
    • 资助金额:
      $2.66万
    • 财政年份:
      2011
    • 负责人:
      HOSOYA Ken
    • 依托单位:
    Development of Recycling-oriented, Antibacterial Environmental Cleanup System based on Natural Function
    Group recognition for Natural Toxic Compounds based on Their Toxicity and Its Contribution to Rapid Analysis
    • 批准号:
      13640604
    • 项目类别:
      Grant-in-Aid for Scientific Research (C)
    • 资助金额:
      $2.24万
    • 财政年份:
      2001
    • 负责人:
      HOSOYA Ken
    • 依托单位:
    Novel recognition methods for environmental hormones based on spatial multi-points interaction
    • 批准号:
      11640608
    • 项目类别:
      Grant-in-Aid for Scientific Research (C)
    • 资助金额:
      $2.18万
    • 财政年份:
      1999
    • 负责人:
      HOSOYA Ken
    • 依托单位:
    海外基金