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Roles of prostanoids in the pathogenesis of cardiovascular diseases

Roles of prostanoids in the pathogenesis of cardiovascular diseases
前列腺素在心血管疾病发病机制中的作用
批准号:
19390060
负责人:
USHIKUBI Fumitaka
金额:
$11.81万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (B)
财政年份:
2007
资助国家:
日本
项目状态:
已结题
起止时间:
2007 至 2009

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中文摘要
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英文摘要
We intended to clarify the roles of prostanoids in the pathogenesis of cardiovascular diseases using mice lacking each prostanoid receptor and murine model of cardiovascular diseases. We clarified the cardioprotective effect of PGE_2 and the suppressive effect of PGI_2 on vascular remodeling. We also found an anti-platelet effect of PGE_2 via EP4 receptor.
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DOI: --
发表时间: 2010-04
期刊: International angiology : a journal of the International Union of Angiology
影响因子: --
作者: [Koh-ichi Yuhki;H. Kashiwagi;Fumiaki Kojima;J. Kawabe;F. Ushikubi]
通讯作者: Koh-ichi Yuhki;H. Kashiwagi;Fumiaki Kojima;J. Kawabe;F. Ushikubi
DOI: 10.1161/atvbaha.109.193730
发表时间: 2010-03-01
期刊: ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
影响因子: 8.7
作者: [Kawabe, Jun-ichi, Yuhki, Koh-ichi, Ushikubi, Fumitaka]
通讯作者: Ushikubi, Fumitaka
Regulation of cardiac prostanoid synthesis by glucocorticoid and its pathophysiological meaning
  • 批准号:
    25670124
  • 项目类别:
    Grant-in-Aid for Challenging Exploratory Research
  • 资助金额:
    $2.5万
  • 财政年份:
    2013
  • 负责人:
    USHIKUBI Fumitaka
  • 依托单位:
Roles of the prostanoids in the regulation of immunological responses
  • 批准号:
    23659130
  • 项目类别:
    Grant-in-Aid for Challenging Exploratory Research
  • 资助金额:
    $2.41万
  • 财政年份:
    2011
  • 负责人:
    USHIKUBI Fumitaka
  • 依托单位:
Roles of the prostanoids in the pathogenesis of cardiovascular diseases
  • 批准号:
    22390045
  • 项目类别:
    Grant-in-Aid for Scientific Research (B)
  • 资助金额:
    $11.9万
  • 财政年份:
    2010
  • 负责人:
    USHIKUBI Fumitaka
  • 依托单位:
Roles of prostanoids in cardiovascular system revealed from studies using knockout mice
  • 批准号:
    14370049
  • 项目类别:
    Grant-in-Aid for Scientific Research (B)
  • 资助金额:
    $9.41万
  • 财政年份:
    2002
  • 负责人:
    USHIKUBI Fumitaka
  • 依托单位:
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