Roles of the prostanoids in the regulation of immunological responses
Roles of the prostanoids in the regulation of immunological responses
批准号:
23659130
负责人:
USHIKUBI Fumitaka
金额:
$2.41万
依托单位国家:
日本
项目类别:
Grant-in-Aid for Challenging Exploratory Research
财政年份:
2011
资助国家:
日本
项目状态:
已结题
起止时间:
2011 至 2012
中文摘要
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英文摘要
To clarify the roles of the prostanoids in the regulation of immunological responses, we employed two animal models showing pathophysiology dependent on immunological responses; renal interstitial fibrosis and Con A-induced hepatitis. Through the analysis of these animal models, we found novel roles and action mechanisms of the PGE2-EP4 system in the development of renal interstitial fibrosis and Con A-induced hepatitis._4
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
Roles of prostanoids in the pathogenesis of cardiovascular system: Novel insights from knockout mouse studies
前列腺素类药物在心血管系统发病机制中的作用:基因敲除小鼠研究的新见解
DOI:
--
发表时间:
2011
期刊:
Pharmacol Ther
影响因子:
--
作者:
[Yuhki K, Kojima F, Kashiwagi H, Ushikubi F, et al]
通讯作者:
et al
DOI:
10.1007/s00535-012-0718-5
发表时间:
2013-08
期刊:
Journal of Gastroenterology
影响因子:
6.3
作者:
[Md. Rafiqul Islam Khan;A. Anisuzzaman;S. Semba;Yanju Ma;Junsuke Uwada;H. Hayashi;Yuichi Suzuki;T. Takano;H. Ikeuchi;M. Uchino;A. Maemoto;F. Ushikubi;I. Muramatsu;T. Taniguchi]
通讯作者:
Md. Rafiqul Islam Khan;A. Anisuzzaman;S. Semba;Yanju Ma;Junsuke Uwada;H. Hayashi;Yuichi Suzuki;T. Takano;H. Ikeuchi;M. Uchino;A. Maemoto;F. Ushikubi;I. Muramatsu;T. Taniguchi
Regulation of cardiac prostanoid synthesis by glucocorticoid and its pathophysiological meaning
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批准号:25670124
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项目类别:Grant-in-Aid for Challenging Exploratory Research
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资助金额:$2.5万
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财政年份:2013
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负责人:USHIKUBI Fumitaka
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依托单位:
Roles of the prostanoids in the pathogenesis of cardiovascular diseases
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批准号:22390045
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$11.9万
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财政年份:2010
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负责人:USHIKUBI Fumitaka
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依托单位:
Roles of prostanoids in the pathogenesis of cardiovascular diseases
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批准号:19390060
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$11.81万
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财政年份:2007
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负责人:USHIKUBI Fumitaka
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依托单位:
Roles of prostanoids in cardiovascular system revealed from studies using knockout mice
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批准号:14370049
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$9.41万
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财政年份:2002
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负责人:USHIKUBI Fumitaka
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依托单位:
Identification of the receptor, which mediates the tumor promoting effect of prostanoids, using knock-out mice.
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批准号:11138202
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项目类别:Grant-in-Aid for Scientific Research on Priority Areas (A)
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资助金额:$6.4万
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财政年份:1999
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负责人:USHIKUBI Fumitaka
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依托单位:
Roles of prostanoids in cardiovascularsystem revealed from studies using knockout mice
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批准号:11470020
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$9.34万
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财政年份:1999
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负责人:USHIKUBI Fumitaka
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依托单位:
Physiological and Pathophysiological roles of prostanoids revealed from studies using mice lacking their receptors
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批准号:11694269
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$4.22万
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财政年份:1999
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负责人:USHIKUBI Fumitaka
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依托单位:
Generation and analysis of mice lacking the prostanoid receptor
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批准号:07557175
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项目类别:Grant-in-Aid for Scientific Research (A)
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资助金额:$9.92万
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财政年份:1995
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负责人:USHIKUBI Fumitaka
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依托单位:
Analysis of the signal transduction pathway through the thromboxane A_2 receptor using the receptor-G-protein reconstitution system
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批准号:05670121
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项目类别:Grant-in-Aid for General Scientific Research (C)
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资助金额:$1.28万
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财政年份:1993
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负责人:USHIKUBI Fumitaka
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依托单位:
海外基金