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An imaging and drug delivary system for treatment of oral cancer by using ultrasound and nano-bubbles

An imaging and drug delivary system for treatment of oral cancer by using ultrasound and nano-bubbles
利用超声波和纳米气泡治疗口腔癌的成像和药物输送系统
批准号:
19390507
负责人:
MORI Shiro
金额:
$12.15万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (B)
财政年份:
2007
资助国家:
日本
项目状态:
已结题
起止时间:
2007 至 2009

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中文摘要
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英文摘要
In the present study, we try to develop a three-dementional imaging system and drug delivery system by using nanobubbles and ultrasound for diagnosis and treatment of oral cancer. As a result, we could make three-dementional ultrasound imaging of neovascularization in small tumor, which could not be detectable by using conventional imaging system such as CT or MRI. Moreover, when the treatment experiment of tumor by the drug delivery system that used the nanobubbles and ultrasound was done, the therapeutic gain by this method was able to be confirmed.
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Local gene delivery system of nano/microbubbles-enhanced ultrasound aimed for treatment of gingival tumor
纳米/微泡增强超声局部基因递送系统旨在治疗牙龈肿瘤
DOI: --
发表时间: 2008
期刊:
影响因子: --
作者: [Chen R, Chiba M, Watanabe Y, Horie S, Tomita N, Fukumoto M, Mori S, Kodama T.]
通讯作者: Kodama T.
Targeted gene delivery using nanobubble and ultrasound.
使用纳米气泡和超声波进行靶向基因递送。
DOI: --
发表时间: 2010
期刊:
影响因子: --
作者: [Teramoto, et al., 小玉哲也]
通讯作者: 小玉哲也
表在性膀胱がんに対する薬剤送達法の開発
浅表性膀胱癌给药方法的开发
DOI: --
发表时间: 2009
期刊:
影响因子: --
作者: [小玉哲也]
通讯作者: 小玉哲也
PET imaging of Na/I symporter gene expression induced by nanobubbles and ultrasound
纳米气泡和超声诱导的 Na/I 同向转运体基因表达的 PET 成像
DOI: --
发表时间: 2010
期刊:
影响因子: --
作者: [Watanabe Y, Horie S, Funaki Y, Kikuchi Y, Yamazaki H, Ishii K, Mori S, Kodama T]
通讯作者: Kodama T
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