Clinicopathological role of kl-6/muc1 with selectin ligand
Clinicopathological role of kl-6/muc1 with selectin ligand
批准号:
19590898
负责人:
YOKOYAMA Akihito
金额:
$2.91万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
2007
资助国家:
日本
项目状态:
已结题
起止时间:
2007 至 2009
中文摘要
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英文摘要
KL-6/MUC1 is a sensitive biomarker for interstitial pneumonias. We found KL-6/MUC1mucins with selectin ligand (designated as SLAK). SLAK was found to be significantly elevated in ARDS patients. Furthermore, SLAK was discovered to be a sensitive, specific and independent predictor for DIC complication in ARDS. Therefore, measurement of SLAK level at diagnosis may be able to predict accurately future complications of DIC in ARDS. Early intervention with anti-DIC medication such as low-molecular-weight heparin in the patients with elevated level of SLAK may improve the prognosis of ARDS, which is currently extremely poor.
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DOI:
10.1136/thx.2009.119974
发表时间:
2010-04-01
期刊:
THORAX
影响因子:
10
作者:
[Senoo, Tadashi, Hattori, Noboru, Kohno, Nobuoki]
通讯作者:
Kohno, Nobuoki
Immunohistochemi cal localization of surfactant proteins A and D, and KL-6 in pulmonary alveolar protei nos is.
肺泡蛋白中表面活性蛋白 A 和 D 以及 KL-6 的免疫组织化学定位。
DOI:
--
发表时间:
2008
期刊:
Pathology 40
影响因子:
--
作者:
[Ohtstuki Y, Kobayashi, M, Yoshida. S, Ki shi mot-N, Kubo K, Yokoyama A, Lee G-H, Furihata, M]
通讯作者:
M
「正常構造」「好酸球性肺炎」「肺性心」「アスピリン喘息」ほか。「まんがで読み解く呼吸器疾患100」(河野修興監修、横山彰仁、服部登編)
「正常结构」、「嗜酸性粒细胞性肺炎」、「肺心病」、「阿司匹林哮喘」等。
DOI:
--
发表时间:
2009
期刊:
影响因子:
--
作者:
[Nakashima T, Yokoyama A, et. al., 横山彰仁, 横山彰仁, 横山彰仁, 横山彰仁]
通讯作者:
横山彰仁
DOI:
10.1016/j.freeradbiomed.2009.01.017
发表时间:
2009-04-15
期刊:
FREE RADICAL BIOLOGY AND MEDICINE
影响因子:
7.4
作者:
[Tanimoto, Takuya, Hattori, Noboru, Kohno, Nobuoki]
通讯作者:
Kohno, Nobuoki
DOI:
--
发表时间:
2010
期刊:
影响因子:
--
作者:
[山根 高]
通讯作者:
山根 高
共 16 条
Development real-time position detection systemof single-ion hit utilizing photostimulated luminescence
-
批准号:23760837
-
项目类别:Grant-in-Aid for Young Scientists (B)
-
资助金额:$2.83万
-
财政年份:2011
-
负责人:YOKOYAMA Akihito
-
依托单位:
Approaches to the pathogenesis of bronchial asthma
-
批准号:13670603
-
项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$2.37万
-
财政年份:2001
-
负责人:YOKOYAMA Akihito
-
依托单位:
Murine models of pulmonary diseases induced by adoptive transfer of T cell clones.
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批准号:05807053
-
项目类别:Grant-in-Aid for General Scientific Research (C)
-
资助金额:$1.22万
-
财政年份:1993
-
负责人:YOKOYAMA Akihito
-
依托单位:
海外基金