Analysis of complement activation in MASP-deficient mice
Analysis of complement activation in MASP-deficient mice
批准号:
19770113
负责人:
IWAKI Daisuke
金额:
$2.52万
依托单位国家:
日本
项目类别:
Grant-in-Aid for Young Scientists (B)
财政年份:
2007
资助国家:
日本
项目状态:
已结题
起止时间:
2007 至 2009
中文摘要
点击翻译按钮获取中文摘要
英文摘要
MASP-1 and MASP-2 are known to cleave some complement components and contribute to activation of the complement system. On the other hand, the function of MASP-3 remains unclear. To further clarify the roles of MASPs we generated and analyzed 3 types of MASP-deficient mice. In this study, we found a way to activate MASP-3 and the protease might be involved in activation of the alternative complement pathway.
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
登录
查看更多内容
Activation of mannose-binding lectin-associated serine protease 3.
甘露糖结合凝集素相关丝氨酸蛋白酶的激活 3。
DOI:
--
发表时间:
2008
期刊:
影响因子:
--
作者:
[D. Iwaki, K. Kanno, M. Takahashi, Y. Endo, M. Matsushita, T. Fujita]
通讯作者:
T. Fujita
DOI:
10.4049/jimmunol.180.9.6132
发表时间:
2008-05-01
期刊:
JOURNAL OF IMMUNOLOGY
影响因子:
4.4
作者:
[Takahashi, Minoru, Iwaki, Daisuke, Fujita, Teizo]
通讯作者:
Fujita, Teizo
Mannose-binding lectin-associated serone protease 3(MASP-3)の機能解析
甘露糖结合凝集素相关丝氨酸蛋白酶 3 (MASP-3) 的功能分析
DOI:
--
发表时间:
2008
期刊:
影响因子:
--
作者:
[Futai, E., Yagishita, S., and Ishiura, S., 岩城大輔]
通讯作者:
岩城大輔
Essential role of mannose-binding lectin-associated serine protease-1 in activation of the complement factor
甘露糖结合凝集素相关丝氨酸蛋白酶-1 在补体因子激活中的重要作用
DOI:
--
发表时间:
2010
期刊:
D.J. Exp. Med. 207
影响因子:
--
作者:
[M. Takahashi, Y. Ishida, D. Iwaki, K. Kanno, T. Suzuki, Y. Endo, Y. Homma, T. Fujita]
通讯作者:
T. Fujita
海外基金