Investigation of mechanisms for the maintenance of cell polarity in epithelial and neuronal cells
Investigation of mechanisms for the maintenance of cell polarity in epithelial and neuronal cells
批准号:
19770160
负责人:
SATO Takashi
金额:
$2.43万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Young Scientists (B)
财政年份:
2007
资助国家:
日本
项目状态:
已结题
起止时间:
2007 至 2008
中文摘要
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英文摘要
細胞極性の維持には、蛋白質を各々の細胞膜領域へと運ぶ極性輸送が必須である。今までに作製した様々な極性輸送制御分子のKOマウスのうち、Rab8aKOマウスは小腸上皮細胞のapicalへの輸送に異常が現れ、微絨毛萎縮症との関連も示唆された。本研究では、Rab8aに類似したRab8bの機能の解明のため、Rab8b欠損マウスと、Rab8aとRab8bの両方を欠損するマウスの解析を行った。また、apical輸送におけるRab8aの分子機序解明のため、Rab8aと他のapical輸送関連分子の間での相互作用の検討も行った。
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DOI:
--
发表时间:
期刊:
影响因子:
--
作者:
[]
通讯作者:
Involvement of proton-sensing TDAG8 in extracellular acidification-induced inhibition of proinflamrnatory cytokine production in peritoneal macrophages
质子感应 TDAG8 参与细胞外酸化诱导的腹膜巨噬细胞促炎细胞因子产生的抑制
DOI:
--
发表时间:
2009
期刊:
The journal of immunology 182
影响因子:
--
作者:
[Kato Y, Sugiura T, Nakadera Y, Sugiura M, Kubo Y, Sato T, Harada A, and Tsuji A, Yukio Kato, Hisanobu Sadakata, Chihiro Mogi]
通讯作者:
Chihiro Mogi
Investigation of the role of oligopeptide transporter PEPT1 and sodium/glucose cotransporter SGLT1 in intestinal absorption of their substrates using small GTP-binding nrotein Rab8-null mice
使用小型 GTP 结合蛋白 Rab8 缺失小鼠研究寡肽转运蛋白 PEPT1 和钠/葡萄糖协同转运蛋白 SGLT1 在其底物肠道吸收中的作用
DOI:
--
发表时间:
2009
期刊:
Drug metabolism and disposition 37
影响因子:
--
作者:
[Kato Y, Sugiura T, Nakadera Y, Sugiura M, Kubo Y, Sato T, Harada A, and Tsuji A, Yukio Kato]
通讯作者:
Yukio Kato
DOI:
10.1097/wnr.0b013e3282fb7d99
发表时间:
2008-04-16
期刊:
NEUROREPORT
影响因子:
1.7
作者:
[Moto, Yukiko Hashi, Muramatsu, Kazuhiro, Harada, Akihiro]
通讯作者:
Harada, Akihiro
Rab8は小腸上皮におけるアピカル蛋白の局在と微絨毛の維持に必須である
Rab8 对于小肠上皮细胞顶端蛋白定位和微绒毛维持至关重要
DOI:
--
发表时间:
2008
期刊:
影响因子:
--
作者:
[Fujio K, Sato M, Uemura T, Sato T, Sato-Harada R, amd Harada A, Takashi Sato, Keisuke Yamamoto, Katsunori Fujio, 佐藤隆史, 佐藤隆史]
通讯作者:
佐藤隆史
共 15 条
Peptide ligand screening of transthyretin protein-protein interaction inhibitor using phage display system
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批准号:16K18875
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项目类别:Grant-in-Aid for Young Scientists (B)
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资助金额:$2.58万
-
财政年份:2016
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负责人:SATO Takashi
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依托单位:
Study of nanoparticles-incorporating immune modulating oligodeoxynucleotide for the treatment of lung diseases
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批准号:15K09224
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$3.08万
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财政年份:2015
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负责人:SATO Takashi
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依托单位:
Evolution of the new competition policy by the open source strategy
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批准号:25380313
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.5万
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财政年份:2013
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负责人:SATO Takashi
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依托单位:
Development of drugs targeting secretory inhibition of transthyretin for familial amyloidotic polyneuropathy
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批准号:24790079
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项目类别:Grant-in-Aid for Young Scientists (B)
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资助金额:$2.91万
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财政年份:2012
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负责人:SATO Takashi
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依托单位:
Study of inhaled nanoparticles incorporating synthetic oligodeoxynucleotides to treat lung diseases
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批准号:23790917
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项目类别:Grant-in-Aid for Young Scientists (B)
-
资助金额:$2.75万
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财政年份:2011
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负责人:SATO Takashi
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依托单位:
A Study in Dynamics of BEI Expression in 3 Prefectures in Northern Kanto Region
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批准号:23520564
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$1.08万
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财政年份:2011
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负责人:SATO Takashi
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依托单位:
Investigation for the nuculear receptor functions to cure clonic inflammatory syndrome
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批准号:23591347
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项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$2.75万
-
财政年份:2011
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负责人:SATO Takashi
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依托单位:
Stabilization and Emergence of Rule Dynamics in Dynamic Cognitive Agents with Internal Dynamics
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批准号:22700242
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项目类别:Grant-in-Aid for Young Scientists (B)
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资助金额:$2.5万
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财政年份:2010
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负责人:SATO Takashi
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依托单位:
Oscillation characteristics improvement of a Vertical Cavity Surface Emitting Laser and consideration to its application
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批准号:22560035
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.83万
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财政年份:2010
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负责人:SATO Takashi
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依托单位:
Molecular mechanisms of gefitinib-induced rash formation: Gefitinib augments lipogenesis and steroidgenesis in sebaceous glands
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批准号:22590506
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.75万
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财政年份:2010
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负责人:SATO Takashi
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依托单位:
Acceleration of Timing Analysis using Monte Carlo Methods
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批准号:22360143
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$12.06万
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财政年份:2010
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负责人:SATO Takashi
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依托单位:
Development of inhaled biodegradable nano/micro-particles incorporated immuno-modulatory DNA for treatment of inflammatory lung diseases
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批准号:21790778
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项目类别:Grant-in-Aid for Young Scientists (B)
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资助金额:$2.75万
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财政年份:2009
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负责人:SATO Takashi
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依托单位:
A History of Modern Jewish Thought and Radical Historicality : Comparative Studies of Franz Rosenzweig and Leo Strauss
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批准号:20720019
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项目类别:Grant-in-Aid for Young Scientists (B)
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资助金额:$1.0万
-
财政年份:2008
-
负责人:SATO Takashi
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依托单位:
Advance of a new decision theory involving cognition process of agent in economics and game theory
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批准号:20830095
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项目类别:Grant-in-Aid for Young Scientists (Start-up)
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资助金额:$0.83万
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财政年份:2008
-
负责人:SATO Takashi
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依托单位:
Effect of irrigated paddy rice and upland crop rotation on diversity of soybean rhizobia.
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批准号:19780049
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项目类别:Grant-in-Aid for Young Scientists (B)
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资助金额:$2.41万
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财政年份:2007
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负责人:SATO Takashi
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依托单位:
Integrated research on history of art craft and archaeology that studies on Zeze-Yaki to clarify a process of establishment of Kansai ceramic technology
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批准号:18520111
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.66万
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财政年份:2006
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负责人:SATO Takashi
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依托单位:
A Research on the Problems of Education and the Process and Requirement for the Development of Teacher Professionalism in this modern society
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批准号:17530617
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$1.66万
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财政年份:2005
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负责人:SATO Takashi
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依托单位:
Policy Designs for Environmental Quality and Fertility
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批准号:16530215
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$1.15万
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财政年份:2004
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负责人:SATO Takashi
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依托单位:
Studies on the mechanism for generation of factors regulating formation and stabilization of plaques in atherosclerosis.
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批准号:15590079
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$1.92万
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财政年份:2003
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负责人:SATO Takashi
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依托单位:
Identification of Human facilitating cells
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批准号:13670807
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项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$1.66万
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财政年份:2001
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负责人:SATO Takashi
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依托单位:
海外基金