Multi-synaptic cortical organization for stereopsis of macaque

用于猕猴立体视觉的多突触皮质组织

• 批准号: 19790162
• 负责人: SAWAMURA Hiromasa
• 金额: $ 2.38万
• 依托单位: The University of Tokyo
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Young Scientists (B)
• 财政年份: 2007
• 资助国家: 日本
• 起止时间: 2007 至 2009
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-19790162/
• 关键词: 大脳皮質視覚領域; 狂犬病ウイルス; 立体視

The primate visual system is characterized by two principal rules : parallel (dorsal and ventral) pathways and hierarchic signal processing. It is well accepted that the information for stereopsis is processed not only in the dorsal cortical areas but also ventral cortical areas. However, multi-synaptic architecture of these two pathways is poorly understood. Within these parallel pathways, MT and V4 are recognized as being situated at a similar hierarchical rank. To re-evaluate the hierarchic relationship between MT and V4, the patterns of retrograde transneuronal labeling in V1 and LGN were analyzed after rabies virus injections into MT and V4 of macaque monkeys. The present results suggest that MT and V4 may be posited at different hierarchic ranks in signal processing in the dorsal and ventral pathways by way of LGN and layer 4C of V1. Moreover, there may be another pathway linking LGN and MT or LGN and V4. It is likely that converging M and P inputs from LGN may contribute to signal processing in these "short-cut" pathways.

灵长类动物的视觉系统的特点是两个主要的规则：平行（背侧和腹侧）的途径和分层的信号处理。人们普遍认为，立体视觉信息不仅在背侧皮层区进行加工，而且在腹侧皮层区也进行加工。然而，这两条通路的多突触结构知之甚少。在这些平行通路中，MT和V4被认为位于相似的等级。为了重新评估MT和V4之间的层次关系，在注射狂犬病病毒后，分析了V1和LGN的逆行跨神经元标记模式。结果提示，MT和V_4在背侧和腹侧通路中通过LGN和V_1的4C层进行信号处理时可能处于不同的层次。此外，可能存在连接LGN和MT或LGN和V4的另一途径。可能的是，来自LGN的M和P输入的收敛可能有助于这些“捷径”途径中的信号处理。

项目成果

Organization and Circuitry in Extrastriate Cortex

纹状体外皮层的组织和电路

• 发表时间: 2009
• 作者: 二宮太平、澤村裕正;et al
• 通讯作者: et al

LGNからV4、MTへの多シナプス性入力様式

从 LGN 到 V4 和 MT 的多突触输入模式

• 发表时间: 2009
• 作者: Ninomiya T;Sawamura H;Inoue K;Takada M.;Ninomiya T.;平田快洋;山崎吉之;高良沙幸;雁木美衣;二宮太平
• 通讯作者: 二宮太平