Architecture of top-down signals conveyed toward extrastriate cortex revealed by rabies virus in the macaque monkey.

狂犬病病毒揭示了猕猴中向纹外皮层传递的自上而下信号的结构。

• 批准号: 22790202
• 负责人: SAWAMURA Hiromasa
• 金额: $ 2.25万
• 依托单位: The University of Tokyo
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Young Scientists (B)
• 财政年份: 2010
• 资助国家: 日本
• 起止时间: 2010 至 2012
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-22790202/
• 关键词: 大脳視覚野; 狂犬病ウイルス; マカクサル

We investigated the architecture of multi-synaptic top-down pathways toward visual area4 (V4) of ventral stream and visual area 5 (MT/V5) of dorsal stream, employing retrograde trans-synaptic transport of rabies virus. In addition, multi-synaptic architecture from the medial temporal lobe to V4 was also investigated. We found that frontal inputs to MT/V5 and V4 mainly arise from area 46v. In addition, we found shot-cut pathway from the hippocampus proper to V4. These results indicate that multi-synaptic architecture may provide top-down information about object recognition accomplished throughoccipito-temporal and occipito-parietal pathways.

我们采用狂犬病毒的逆行跨突触转运研究了腹侧流视区4（V4）和背侧流视区5（MT/V5）的多突触自上而下通路的结构。此外，还研究了从内侧颞叶到V4的多突触结构。我们发现MT/V5和V4的额叶输入主要来自46 v区。此外，我们发现了从海马到V4的shot-cut通路。这些结果表明，多突触结构可能提供自上而下的信息，通过枕颞和枕顶途径完成的物体识别。

项目成果

サイトメガロ虹彩炎の再発回数

巨细胞虹膜炎复发次数

• 发表时间: 2010
• 作者: Mari GOTOH;Norito KOTANI;Munehisa TAKAHASHI;Tomoko OKADA;Yoshikatsu OGAWA;澤村裕正
• 通讯作者: 澤村裕正

Case of metastatic pulmonary carcinoma in optic disc diagnosed from results of biopsy performed during vitrectomy surgery

• DOI: 10.1007/s00417-011-1770-1
• 发表时间: 2011-12-01
• 期刊: GRAEFES ARCHIVE FOR CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY
• 影响因子: 2.7
• 作者: Fukuda, Reina;Tanabe, Tatsuro;Kaburaki, Toshikatsu
• 通讯作者: Kaburaki, Toshikatsu

Differential Architecture of Multisynaptic Geniculo-Cortical Pathways to V4 and MT

• DOI: 10.1093/cercor/bhr078
• 发表时间: 2011-12-01
• 期刊: CEREBRAL CORTEX
• 影响因子: 3.7
• 作者: Ninomiya, Taihei;Sawamura, Hiromasa;Takada, Masahiko
• 通讯作者: Takada, Masahiko

Deficits in Action Selection Based on Numerical Information After Inactivation of the Posterior Parietal Cortex in Monkeys

• DOI: 10.1152/jn.01014.2009
• 发表时间: 2010-08-01
• 期刊: JOURNAL OF NEUROPHYSIOLOGY
• 影响因子: 2.5
• 作者: Sawamura, Hiromasa;Shima, Keisetsu;Tanji, Jun
• 通讯作者: Tanji, Jun

Multisynaptic inputs from the medial temporal lobe to V4 in macaques.

• DOI: 10.1371/journal.pone.0052115
• 发表时间: 2012
• 期刊: PloS one
• 影响因子: 3.7
• 作者: Ninomiya T;Sawamura H;Inoue K;Takada M
• 通讯作者: Takada M