Screening of the host evasion-related genes in schistosome by RNA interference.
Screening of the host evasion-related genes in schistosome by RNA interference.
批准号:
19790305
负责人:
KUMAGAI Takashi
金额:
$2.37万
依托单位国家:
日本
项目类别:
Grant-in-Aid for Young Scientists (B)
财政年份:
2007
资助国家:
日本
项目状态:
已结题
起止时间:
2007 至 2009
中文摘要
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英文摘要
Schistosoma japonicum is the parasitic platehelminth living in the bloodstreem of host. As this worm have the evasion systems from the host immune systems, vaccine development is not achieved in this field. In the present study, we screened the genes related to these immune evasions using RNAi screening method targeting the specific genes in early infectious stage. As the result of 1st screening, we found 3 genes related to the resistance against nitric oxide, and 8 essential genes for survive.
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新規抗住血吸虫剤
抗血吸虫新药
DOI:
--
发表时间:
2008
期刊:
影响因子:
--
作者:
[]
通讯作者:
RNA干渉の日本住血吸虫にとっての意義とは何か? ~環境dsRNAの取込みという視点から~
RNA干扰对日本血吸虫有何意义?~从环境dsRNA的摄取角度~
DOI:
--
发表时间:
2009
期刊:
影响因子:
--
作者:
[熊谷貴, ら]
通讯作者:
ら
Direct gene suppression of peroxiredoxins from Schistosoma japonicum in the portal vein by in vivo RNA interference
通过体内 RNA 干扰对门静脉中日本血吸虫过氧化还原蛋白的直接基因抑制
DOI:
--
发表时间:
2008
期刊:
影响因子:
--
作者:
[Takahi Kumagai, et al]
通讯作者:
et al
DOI:
10.2149/tmh.2009-24
发表时间:
2010-01-01
期刊:
Tropical Medicine and Health
影响因子:
4.5
作者:
[Anyan, W. K., Kumagai, T., Ohta, N.]
通讯作者:
Ohta, N.
Molecular characterizations and functions of systemic RNAi deficiency-1 from Schistosoma japonicum
日本血吸虫全身性RNAi缺陷-1的分子特征和功能
DOI:
--
发表时间:
2009
期刊:
影响因子:
--
作者:
[熊谷貴, 他]
通讯作者:
他
Functional analysis for sexual maturation in extracellular vesicles using miRNA knockdown schistosomes
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批准号:16K08756
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$3.08万
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财政年份:2016
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负责人:KUMAGAI Takashi
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依托单位:
Towards de Giorgi-Nash-Moser theory on non-linear non-local partial differential equations.
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批准号:24654033
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资助金额:$2.41万
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财政年份:2012
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负责人:KUMAGAI Takashi
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依托单位:
Immunosuppressions by extracellular vesicles secreted from Schistosoma japonicum
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批准号:24590503
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$3.41万
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财政年份:2012
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负责人:KUMAGAI Takashi
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依托单位:
The host RNA uptake related gene in Schistosoma japonicum
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批准号:22790393
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项目类别:Grant-in-Aid for Young Scientists (B)
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资助金额:$2.66万
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财政年份:2010
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负责人:KUMAGAI Takashi
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依托单位:
Markov chains on disordered media and their scaling limits
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批准号:22340017
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$10.73万
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财政年份:2010
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负责人:KUMAGAI Takashi
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依托单位:
Developments of the theory of stochastic processes and real analysis on disordered media
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批准号:18340027
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$8.68万
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财政年份:2006
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负责人:KUMAGAI Takashi
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依托单位:
INteraction between probability and analysis on disordered media
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批准号:14540113
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.62万
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财政年份:2002
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负责人:KUMAGAI Takashi
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依托单位:
Analysis of sample paths for stochastic processes
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批准号:11640713
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.24万
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财政年份:1999
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负责人:KUMAGAI Takashi
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依托单位:
Research of stochastic processes on fractals.
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批准号:08454040
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$1.15万
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财政年份:1996
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负责人:KUMAGAI Takashi
-
依托单位:
海外基金