Development of aesthetic light-activated restorative resin using a new photoinitiation system

可见光活化复合树脂由于其易于处理、美观、改善的物理和机械性能而被广泛用于牙科作为直接填充修复材料。考虑到紫外光的不良生物效应，使用邻苯二酚（CQ）作为可见光活化树脂的光引发剂已被牙科接受，因为它吸收无害的可见蓝光区域的波长。然而，CQ具有一些缺点，例如低聚合效率和其固体黄色，这将导致树脂的低机械性能，并导致最终聚合树脂的不期望的泛黄。这对树脂中CQ的可接受浓度施加了实际限制。为了克服CQ的缺点，已经引入了一些替代的可见光光引发剂作为牙科光活化树脂的光引发剂，这些光引发剂与CQ相比具有诸如较低的泛黄效应和较高的聚合效率等期望的益处。本研究调查了替代的各种新的光引发剂，如苯基丙二酮，单酰基氧化膦，和双酰基氧化膦，这将取代CQ而不降低树脂的性能的有效性。此外，光活化树脂上的替代光引发剂的颜色效果进行了比较，CQ。我们的研究结果表明，单酰基氧化膦光引发剂为牙科光活化树脂提供了一个有用的和改进的光聚合体系，并且与CQ和其他光引发剂相比，在聚合过程中和聚合后的颜色变化也较小。

Visible light-activated composite resins has been widely used in dentistry as direct filling restorative materials because of their easy handling, aesthetics, and improved physical and mechanical properties. Considering the adverse biological effects of UV light, the use of camphorquinone (CQ) as a photoinitiator for the visible light-activated resin has been accepted in dentistry, because it absorbs wavelengths in the harmless visible blue-light region. However, CQ has some drawbacks such as low polymerization efficiency and its solid yellow, which would result in low mechanical properties of the resin, and lead to undesirable yellowing of the final polymerized resin. This places practical limits on the acceptable concentration of CQ in the resin. To overcome the drawbacks of CQ, some alternative visible light photoinitiators have been introduced for dental light-activated resins as the photoinitiators, which have desirable benefits such as a lower yellowing effect and higher polymerization efficiency compared with CQ. This study investigated the efficacy of alternative various new photoinitiators, such as phenylpropadione, monoacylphosphine oxide, and bisacylphosphine oxide, which would replace CQ without diminishing the properties of resin. In addition, the color effects of the alternative photoinitiators on the light-activated resin were compared to that of CQ. Our results indicate that the monoacylphosphine oxide photoinitiator provided a useful and improved photopolymerization system for dental light-activated resins, and also showed less of a color change during and after polymerization in comparison with CQ and other photoinitiators.