Analysis of structural elements controlling transglycosylation and its application

糖基酶是目前用于生产低聚糖的酶。有趣的是，生产能力取决于糖基酶的种类，这意味着它们的结构元素有助于反应的特异性。我们的研究旨在阐明糖基酶催化的转糖基化的结构要素。我们的研究取得了1)阐明了与低聚糖生产有关的结构元件；Ii)建立低聚糖生产的理论背景；Iii)寻找调节低聚糖产生的途径。

Glycosylases are enzymes, which are currently utilized for the production of oligosaccharides. Interestingly, production-ability is dependent on the kinds of glycosylases, meaning that their structural elements contribute to the reaction specificity. Our research aims at elucidating structural elements of glycosylase-catalyzed transglycosylation. Our research achieved i) elucidation of structural elements contributing to the oligosaccharide production ; ii) establishment of the theoretical background of oligosaccharide production ; iii) finding the ways to regulate the oligosaccharide production.