课题基金 / 基金详情

Novel therapeutic approach to melanoma-bearing hosts with protein-transduction technology

Novel therapeutic approach to melanoma-bearing hosts with protein-transduction technology
利用蛋白质转导技术治疗黑色素瘤宿主的新方法
批准号:
20390306
负责人:
SHIMADA Shinji
金额:
$12.06万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (B)
财政年份:
2008
资助国家:
日本
项目状态:
已结题
起止时间:
2008 至 2010

项目摘要

项目成果

SHIMADA Shinji的其他基金

相似基金

相关文献

中文摘要
翻译
点击翻译按钮获取中文摘要
英文摘要
Protein-transduction domains (PTDs) are short stretches of cationic amino acids that enable peptides, proteins, oligonucleotides, and other reagents to efficiently enter multiple cell types. Therefore, PTDs offer unique therapeutic opportunities for the treatment of many diseases, including malignant melanoma. Intratumoral injections of R9-antigens and R9-containing STAT3 inhibitors can reduce tumor growth in vivo.
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
Intradermal injiections of polyarginin-containing immunogenic antigens preferentially elicit Tc1 and Th1 activation and antitumor immunity
皮内注射含聚精氨酸的免疫原性抗原优先引发 Tc1 和 Th1 激活和抗肿瘤免疫
DOI: --
发表时间: 2010
期刊: British Journal of Dermatology 162
影响因子: --
作者: [H.Mitsui, T.Okamoto, M.Kanzaki, T.Inozume, N Shibagaki, S Shimada]
通讯作者: S Shimada
癌免疫療法のトピックスと展望
癌症免疫治疗的主题和前景
DOI: --
发表时间: 2011
期刊:
影响因子: --
作者: [大川哲平, 遠藤明史, 満生紀子, 青木由貴, 小野敏明, 磯田健志, 富澤大輔, 高木正稔, 梶原道子, 長澤正之, 森尾友宏, 水谷修紀, 柴垣直孝]
通讯作者: 柴垣直孝
Novel Immunotherapeutic approaches to skin cancer treatments using protein transduction technology
使用蛋白质转导技术治疗皮肤癌的新型免疫治疗方法
DOI: 10.1016/j.jdermsci.2010.12.003
发表时间: 2011
期刊: Journal of Dermatological Science
影响因子: 4.6
作者: [柴垣直孝, 島田眞路, NAOTAKA SHIBAGAKI]
通讯作者: NAOTAKA SHIBAGAKI
Intradermal injections of polyarginine-containing immunogenic antigens preferentially elicit Tc1 and Th1 activation and antitumor immunity
皮内注射含聚精氨酸的免疫原性抗原优先引发 Tc1 和 Th1 激活和抗肿瘤免疫
DOI: --
发表时间: 2010
期刊: British Journal of Dermatology
影响因子: 10.3
作者: [H Mitsui, et al.]
通讯作者: et al.
19
    The alarmin IL-33 derived from HSV-2-infected keratinocytes triggers mast cell-mediated antiviral innate immunity
    • 批准号:
      26293256
    • 项目类别:
      Grant-in-Aid for Scientific Research (B)
    • 资助金额:
      $10.65万
    • 财政年份:
      2014
    • 负责人:
      SHIMADA Shinji
    • 依托单位:
    Development of an innovative, simple system to detect the critical gene mutations of skin cancers
    • 批准号:
      26670522
    • 项目类别:
      Grant-in-Aid for Challenging Exploratory Research
    • 资助金额:
      $2.33万
    • 财政年份:
      2014
    • 负责人:
      SHIMADA Shinji
    • 依托单位:
    The elucidation of the early immune system in percutaneous infection of HSV and HIV and the development of novel methods to prevent their cutaneous infection
    • 批准号:
      23390282
    • 项目类别:
      Grant-in-Aid for Scientific Research (B)
    • 资助金额:
      $12.48万
    • 财政年份:
      2011
    • 负责人:
      SHIMADA Shinji
    • 依托单位:
    Examination of the participation in HIV infection of the VitaminD3 and HSV-2 using the humanized mouse
    • 批准号:
      23659545
    • 项目类别:
      Grant-in-Aid for Challenging Exploratory Research
    • 资助金额:
      $2.41万
    • 财政年份:
      2011
    • 负责人:
      SHIMADA Shinji
    • 依托单位:
    海外基金