Functional compensation and independency of two sphingomyelin synthases
Functional compensation and independency of two sphingomyelin synthases
批准号:
20570145
负责人:
WATANABE Ken
金额:
$3.08万
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
2008
资助国家:
日本
项目状态:
已结题
起止时间:
2008 至 2010
中文摘要
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英文摘要
Two sphingomyelin synthase, SMS1 and SMS2, are structurally homologous proteins but exhibit different cellular localization. In this study, mice deficient either for Sms1 or Sms2 gene were generated. Through the phenotypic analyses of Sms1KO and Sms2KO mice, the enzymes partially compensate in sphingomyelin biosynthesis but play different roles in biological aspects and physiology.
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DOI:
--
发表时间:
2010
期刊:
影响因子:
--
作者:
[光武進, 横田はづき, 座間宏太, 山下匡, 岡崎俊朗, 渡辺研, 五十嵐靖之]
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五十嵐靖之
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DOI:
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发表时间:
2009
期刊:
日本臨床 67
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[渡辺研, 池田恭治]
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池田恭治
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DOI:
--
发表时间:
2009
期刊:
影响因子:
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作者:
[座間宏太, 林遥, 光武進, 角南寛, 山下匡, 渡辺研, 岡崎俊郎, 五十嵐靖之]
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五十嵐靖之
DOI:
10.1007/s12018-010-9076-0
发表时间:
2010-11
期刊:
Clinical Reviews in Bone and Mineral Metabolism
影响因子:
1.8
作者:
[Ken Watanabe;K. Ikeda]
通讯作者:
Ken Watanabe;K. Ikeda
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DOI:
--
发表时间:
2010
期刊:
影响因子:
--
作者:
[矢野正人, 山本格士, 渡部研, 池田和貴, 瀬ノ口隆文, 門松毅, 束野寛人, 後藤知己, 岡崎俊朗, 田口良, 山縣和也, 尾池雄一]
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尾池雄一
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