Study on homeostasis of hyperthermophiles

活的微生物面临各种应激，并通过诱导多种应激反应蛋白来保护自己。在所有微生物中，生长在85℃以上的超嗜热微生物被认为是最原始的微生物之一。目前尚不清楚超嗜热菌如何适应环境变化，如温度胁迫和营养缺乏。本文以嗜热古细菌柯达卡兰热球菌（Thermococcus kodakaraensis）为模型微生物，重点分析了嗜热菌对环境变化的适应机制。

Living microorganisms face various kinds of stress and protect themselves by inducing several stress-responsive proteins. Among all microorganism, hyperthemophiles that grow above 85℃ are considered as one of most primitive microorganisms. It is unclear how hyperthermophile adapts to environmental changes such as temperature stress and nutrient starvation. In the present study, adaptation mechanisms of hyperthermophiles to environmental changes were focused and analyzed using hyperthermophilic archaeon Thermococcus kodakaraensis as a model microorganism.