Antiparasitic components newly isolated from red algae for parasitic copepodes of cultured pufferfish

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In aquaculture industry, caligid copepods are well known as pests causing heavy mortality or acting as disease inducers by creating a portal for entry of bacteria or other pathogens. The caligid Pseudocaligus fugu has been causing serious damages on cultured tiger puffer in western Japan. Hence we have tried to search for some antiparasitic agents which cause no damage on the host. Two compounds isolated from crude H_2O extract of "makuri", a red alga Digenea simplex showed effects on the parasite. One was kainic acid(C_<10>H_<15>NO_4, MW=213), and the other one showing the same molecular weight of it.