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Study in the effects of IBM-BMT using parabiotic mice

Study in the effects of IBM-BMT using parabiotic mice
使用联体小鼠研究 IBM-BMT 的效果
批准号:
20590413
负责人:
INABA Muneo
金额:
$3.0万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
2008
资助国家:
日本
项目状态:
已结题
起止时间:
2008 至 2010

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英文摘要
We have prepared the parabiotic mice to compare the efficiency of donor dell engraftment by IBM-BMT with that by IV-BMT in the physiological condition. BMCs from GFP mice were transplanted into C57BL/6 mice by IBM-BMT ([GFP->C57BL/6]^<IBM-BMT>), and the parabiotic mouse was made up of the ([GFP->C57BL/6]^<IBM-BMT> mouse and normal C57BL/6 mouse ([GFP→C57BL/6]^<IBM-BMT>+C57BL/6). In this mouse, the frequency of hemopoietic progenitor cells, defined as Lin^-/c-kit^+ cells, was significantly higher than that determined in the ([GFP→C57BL/6]^<IV-BMT>+C57BL/6 mouse, indicating the efficiency of donor cell engraftment by IBM-BMT.
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DOI: 10.1016/j.jaut.2009.10.002
发表时间: 2010-06-01
期刊: JOURNAL OF AUTOIMMUNITY
影响因子: 12.8
作者: [Hoshino, Shoichi, Inaba, Muneo, Ikehara, Susumu]
通讯作者: Ikehara, Susumu
DOI: 10.1007/s00277-008-0513-9
发表时间: 2008-10-01
期刊: ANNALS OF HEMATOLOGY
影响因子: 3.5
作者: [Kato, Junko, Hisha, Hiroko, Ikehara, Susumu]
通讯作者: Ikehara, Susumu
DOI: --
发表时间: 2009
期刊: Otolaryngol.-Head and Neck Surg. 141
影响因子: --
作者: [Suzuki, K.]
通讯作者: K.
DOI: 10.1097/01.tp.0000296061.71662.76
发表时间: 2008-01-15
期刊: TRANSPLANTATION
影响因子: 6.2
作者: [Guo, Kequan, Inaba, Muneo, Ikehara, Susumu]
通讯作者: Ikehara, Susumu
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