Molecular epidemiologic study on the health effects of exposure to environmental cadmium

点击翻译按钮获取中文摘要

In a meta-analysis of the mortality rate in cadmium-polluted areas, meta-standardized mortality ratio of all-cause was significantly higher than 100 in women, and the summary hazard ratio of all deaths in the group with cadmium-induced renal dysfunction was significantly higher than those without renal dysfunction, in both sexes. Among women, summary hazard ratio of cancer mortality in the group with cadmium-induced renal dysfunction was significantly increased as compared with the group without renal dysfunction. With regard to an epidemiologic study on the effects of cadmium exposure on gene expression signatures in peripheral blood cells, a field study on the exposed group has finished. However, study on the age-matched control group is still under way.