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Effect of intravenous administration of immunoglobulin on myocardial reperfusion injury.

Effect of intravenous administration of immunoglobulin on myocardial reperfusion injury.
静脉注射免疫球蛋白对心肌再灌注损伤的影响。
批准号:
20790547
负责人:
UENO Koji
金额:
$2.66万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Young Scientists (B)
财政年份:
2008
资助国家:
日本
项目状态:
已结题
起止时间:
2008 至 2009

项目摘要

项目成果

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中文摘要
翻译
在缺血/再灌注(I/R)前静脉注射免疫球蛋白(IVIG)预处理可减轻微循环障碍和炎症反应,并保护左心室功能。IVIG可能通过抑制在I/R早期炎性级联反应中起重要作用的补体系统而对心肌再灌注损伤起到持续治疗作用。
英文摘要
Intravenous administration of immunoglobulin (IVIG) pretreatment before ischemia/reperfusion (I/R) attenuated microcirculatory disturbance and inflammatory response, and preserved left ventricular function. IVIG may be effective as an adjunctive therapy to myocardial reperfusion injury, possibly through inhibition of complementary system that plays an important role during the early stage of inflammatory cascades in I/R.
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会议论文
Intravenous administration of immunoglobulin attenuates myocardial reperfusion injury and improves left ventricular remodeling
静脉注射免疫球蛋白可减轻心肌再灌注损伤并改善左心室重构
DOI: --
发表时间: 2007
期刊: Circulation 116(Suppl)
影响因子: --
作者: [Ueno K, Anzai T, Jo Y, Naito K, Kohno T, Takahashi T, Yoshikawa T, Ogawa S.]
通讯作者: Ogawa S.
Development of angiogenic microRNA-contained exosomes for angiogenesis therapy
  • 批准号:
    19K09272
  • 项目类别:
    Grant-in-Aid for Scientific Research (C)
  • 资助金额:
    $2.83万
  • 财政年份:
    2019
  • 负责人:
    UENO Koji
  • 依托单位:
Development of angiogenesis therapy by microRNA expressed in mice with angiogenic ability
  • 批准号:
    17K16593
  • 项目类别:
    Grant-in-Aid for Young Scientists (B)
  • 资助金额:
    $2.58万
  • 财政年份:
    2017
  • 负责人:
    UENO Koji
  • 依托单位:
Analysis of extracellular microRNA having protective effects against ischemia-perfusion injury of organs after ischemic preconditioning
  • 批准号:
    15K19921
  • 项目类别:
    Grant-in-Aid for Young Scientists (B)
  • 资助金额:
    $2.5万
  • 财政年份:
    2015
  • 负责人:
    UENO Koji
  • 依托单位:
海外基金