Establishment of the methods for regeneration of steroidogenic cells from mesencymal stem cells and analysis of its mechanism
Establishment of the methods for regeneration of steroidogenic cells from mesencymal stem cells and analysis of its mechanism
批准号:
20790661
负责人:
TANAKA Tomoko
金额:
$2.75万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Young Scientists (B)
财政年份:
2008
资助国家:
日本
项目状态:
已结题
起止时间:
2008 至 2009
中文摘要
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英文摘要
Although we reported that Ad4BP/SF-1 transformed mesenchymal stem cells (MSCs) into steroidogenic cells, Ad4BP/SF-1-converted steroidogenic cells produce both adrenal-type steroids and gonad-type steroids. To clarify the underlying mechanism, we analyzed the expression profile and focused on the several factors up-regulated by Ad4BP/SF-1. Among these factors, Sfrp-1 and Inhbb might be related to Ad4BP/SF-1-mediated differentiation of MSCs into gonad-type steroidogenic cells.
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Steroidogenic cells regenerated from mesenchymal stem cells
由间充质干细胞再生的类固醇生成细胞
DOI:
--
发表时间:
2010
期刊:
影响因子:
--
作者:
[H. Sirohzu, et.al., Tomoko Tanaka, 田中智子]
通讯作者:
田中智子
Effects of Sfrp-1 and Inhibin beta B on SF-1 mediated differntiation of mesenchymal stem cells into steroidogenic cells
Sfrp-1和抑制素βB对SF-1介导的间充质干细胞向类固醇生成细胞分化的影响
DOI:
--
发表时间:
2010
期刊:
影响因子:
--
作者:
[H. Sirohzu, et.al., Tomoko Tanaka, 田中智子, Tomoko Tanaka]
通讯作者:
Tomoko Tanaka
A novel synthetic androgen receptor ligand, S42, works as a selective androgen receptor modulator and possesses metabolic effects with little impact on the prostate
一种新型合成雄激素受体配体 S42,作为选择性雄激素受体调节剂,具有代谢作用,对前列腺影响很小
DOI:
--
发表时间:
2009
期刊:
Endocrinology 150
影响因子:
--
作者:
[Ariyasu H, Nakao K, et al, Amagai M, Min L]
通讯作者:
Min L
DOI:
10.1210/en.2009-1268
发表时间:
2010-07-01
期刊:
ENDOCRINOLOGY
影响因子:
4.8
作者:
[Qiu, Yang, Yanase, Toshihiko, Nawata, Hajime]
通讯作者:
Nawata, Hajime
間葉系幹細胞からのステロイド産生細胞への分化誘導における性分化関連因子の影響について
性分化相关因子对间充质干细胞向类固醇细胞分化诱导的影响
DOI:
--
发表时间:
2008
期刊:
影响因子:
--
作者:
[田中智子, 他]
通讯作者:
他
共 11 条
The Comprehensive Research on Education Policy under Minister Mori Arinori
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Program development for regular dental check-up promotion
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Social skills as cross-cultural correspondence ability ofhosts for enhancing interpersonal relationship formation.
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Intervention Research of Clinical-Social Psychology by Cross-Cultural Social Skills Learning
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The Research on Future Development Direction of the Station-type Nursery in proportion to the new nurture needs
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海外基金