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Clinicopathological study on functional subdivisions of the globus pallidus internus in dystonias.

Clinicopathological study on functional subdivisions of the globus pallidus internus in dystonias.
肌张力障碍苍白球内部功能分区的临床病理学研究。
批准号:
20591025
负责人:
GOTO Satoshi
金额:
$3.08万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
2008
资助国家:
日本
项目状态:
已结题
起止时间:
2008 至 2010

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中文摘要
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英文摘要
Altered neural activity of the globus pallidus (GP) due to dysregulation of striatal dopamine functions has been proposed as a major cause of dystonia genesis. Based on the clinico-physiological data obtained from the patients with dystonia, we found that abnormal patterned activities of the posteroventral portion of the GPi have a tight link with occurrence o f dystonia symptoms. In addition, our data on the experimental animal models that include tran sgenic mice showed that striatal striosome-matrix dopamine systems could be involved in the dystonia genesis.
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Olfactory type G-protein alpha subunit in striosome-matrix dopamine systems in adult mice.
成年小鼠纹状体基质多巴胺系统中的嗅觉型 G 蛋白 α 亚基。
DOI: --
发表时间: 2010
期刊: Neuroscience
影响因子: 3.3
作者: [Sako W, Morigaki R, Nagahiro S, Kaji R, Goto S.]
通讯作者: Goto S.
Thalamic Deep Brain Stimulation for Parkinson’s Disease
丘脑深部脑刺激治疗帕金森病
DOI: --
发表时间: 2011
期刊:
影响因子: --
作者: [R. Morigaki, Shinji Nagahiro, Ryuji Kaji, Satoshi Goto]
通讯作者: Satoshi Goto
DOI: --
发表时间: 2010
期刊:
影响因子: --
作者: [山崎貴男, et al., 後藤恵, 後藤恵]
通讯作者: 後藤恵
Bilateral pallidal deep brain stimulation in primary Meiges syndrome.
原发性梅格斯综合征的双侧苍白球深部脑刺激。
DOI: --
发表时间: 2011
期刊: Parkinsonism Relat Disord.
影响因子: --
作者: [Sako W, et al.]
通讯作者: et al.
29
    Studies on development of slope disaster risk map evaluating the generation and transfer process of volcaniclastic materials based on the perspectives of eruption history
    • 批准号:
      17H03303
    • 项目类别:
      Grant-in-Aid for Scientific Research (B)
    • 资助金额:
      $10.9万
    • 财政年份:
      2017
    • 负责人:
      GOTO Satoshi
    • 依托单位:
    Experimental study on functional pathology of L-DOPA-induced dyskinesia in Parkinson's disease.
    • 批准号:
      17K07096
    • 项目类别:
      Grant-in-Aid for Scientific Research (C)
    • 资助金额:
      $3.16万
    • 财政年份:
      2017
    • 负责人:
      GOTO Satoshi
    • 依托单位:
    Functional zones in the nuclear envelope and endoplasmic reticulum
    • 批准号:
      16K14731
    • 项目类别:
      Grant-in-Aid for Challenging Exploratory Research
    • 资助金额:
      $2.33万
    • 财政年份:
      2016
    • 负责人:
      GOTO Satoshi
    • 依托单位:
    Experimental study on functional pathology of dystonia
    • 批准号:
      26430054
    • 项目类别:
      Grant-in-Aid for Scientific Research (C)
    • 资助金额:
      $3.33万
    • 财政年份:
      2014
    • 负责人:
      GOTO Satoshi
    • 依托单位:
    海外基金