Studies on the mechanism to gain monocyte chemotactic capacity of ribosomal protein S19 and its role in coagulum resorption.
Studies on the mechanism to gain monocyte chemotactic capacity of ribosomal protein S19 and its role in coagulum resorption.
批准号:
21590441
负责人:
YAMAMOTO Tetsuro
金额:
$3.0万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
2009
资助国家:
日本
项目状态:
已结题
起止时间:
2009 至 2011
中文摘要
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英文摘要
In the present research, we have revealed that ribosomal protein S19(RP S19) present in normal blood plasma is covalently dimerized by activated factor XIII on the activated platelet surface and gains monocyte chemotactic capacity during blood coagulation process, that the RP S19 dimer recruits monocytes to the coagulum resulting in cellular fibrinolytic absorption of the coagulum, and that monocytotic state of peripheral blood enhance the coagulum resorption process.
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Extraribosomal functions of ribosomal protein S19 In Ribosomal Proteins and Protein Engineering : Design, Selection and Applications(Valter Ortendhal, Hjalmar Salchow eds.)
核糖体蛋白 S19 在核糖体蛋白和蛋白质工程中的核糖体外功能:设计、选择和应用(Valter Ortendhal、Hjalmar Salchow 编辑)
DOI:
--
发表时间:
2010
期刊:
影响因子:
--
作者:
[Mitsuru Futakuchi, Masumi Suzui, Katsumi Fukamachi, Rakesh Singh, 石原克彦, T. Yamamoto and H. Nishiura]
通讯作者:
T. Yamamoto and H. Nishiura
Maintenance of ribosomal protein S19 in plasma by complex formation with prothrombin.
通过与凝血酶原形成复合物维持血浆中核糖体蛋白 S19。
DOI:
--
发表时间:
2011
期刊:
European Journal of Haematology
影响因子:
3.1
作者:
[森谷卓也, 鹿股直樹, 周辺病変・免疫染色, Hiroshi Nishiura]
通讯作者:
Hiroshi Nishiura
A molecular mimicry basis on the two-step binding structure to the C5a receptor between ribosomal protein S19 homodimer cross-linked by transglutaminase and C5a anaphylatoxin.
分子模拟基础是通过转谷氨酰胺酶和 C5a 过敏毒素交联的核糖体蛋白 S19 同二聚体与 C5a 受体的两步结合结构。
DOI:
--
发表时间:
2010
期刊:
影响因子:
--
作者:
[Nishiura, H.]
通讯作者:
H.
血漿に含まれるS19リボソームタンパク質様分子の血液凝固に伴う架橋二量体化機構
凝血过程中血浆中S19核糖体蛋白样分子的交联二聚机制
DOI:
--
发表时间:
2009
期刊:
影响因子:
--
作者:
[千場梅子, 甚俊, 太田宜彦, 西浦弘志, 山本哲郎]
通讯作者:
山本哲郎
血漿中のS19リボソームタンパタ質様分子の血液凝固に伴う単球走化活性の獲得と凝血塊除去における役割
血浆中S19核糖体蛋白样分子在获得单核细胞趋化活性和凝血相关血块清除中的作用
DOI:
--
发表时间:
2009
期刊:
影响因子:
--
作者:
[Kosuke Oikawa, Takayuki Hiroi, Shunji Itoh, Ting Gui, Zhibo Gai, Masakatsu Takanashi, Masahiko Kuroda, Yasuteru Muragaki, 太田宜彦]
通讯作者:
太田宜彦
共 21 条
Role of plasma S19 ribosomal protein in thrombus resorption
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批准号:18590374
-
项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$2.57万
-
财政年份:2006
-
负责人:YAMAMOTO Tetsuro
-
依托单位:
Study on evaluation of stability of slope holding discontinuous plane causing slope failure
-
批准号:15560427
-
项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$1.34万
-
财政年份:2003
-
负责人:YAMAMOTO Tetsuro
-
依托单位:
Analysis of CS5 co-receptor molecule that specifically inhibits chemotaxis of polymorphonuclear leukocytes
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批准号:12470058
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$7.62万
-
财政年份:2000
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负责人:YAMAMOTO Tetsuro
-
依托单位:
ELECTROPHY SIOLOGICAL AND MORHPHOLOGICAL STUDIES ON INTERACTION BETWEEN THE CEREBELLAR AND BASAL GANGLIA INPUTS.-ANALYSIS OF INTEGRATION IN THE CEREBRAL CORTEX-
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批准号:11680806
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项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$2.37万
-
财政年份:1999
-
负责人:YAMAMOTO Tetsuro
-
依托单位:
Finite difference and finite element analysis for partial differential equations
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批准号:11440030
-
项目类别:Grant-in-Aid for Scientific Research (B)
-
资助金额:$4.16万
-
财政年份:1999
-
负责人:YAMAMOTO Tetsuro
-
依托单位:
Mathematical analysis of linear/nonlinear iterative algorithms including GMRES, SOR, etc.
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批准号:09640277
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$0.96万
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财政年份:1997
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负责人:YAMAMOTO Tetsuro
-
依托单位:
S19 RIBOSOMAL PROTEIN DIMER AS MONOCYTE CHEMOTACTIC FACTOR IN CHRONIC INFLAMMATION.
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批准号:08457072
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$0.0万
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财政年份:1996
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负责人:YAMAMOTO Tetsuro
-
依托单位:
Studies on the membrane properties of the cat parietal cortical pyramidal neurons concerning motor compensation
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批准号:06680808
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项目类别:Grant-in-Aid for General Scientific Research (C)
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资助金额:$1.41万
-
财政年份:1994
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负责人:YAMAMOTO Tetsuro
-
依托单位:
Studies on The Response and Morphology of The Cortical Neurons using Double Intracellular labeling
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批准号:02670048
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项目类别:Grant-in-Aid for General Scientific Research (C)
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资助金额:$1.41万
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财政年份:1990
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负责人:YAMAMOTO Tetsuro
-
依托单位:
ROLE OF HAGEMAN FACTOR-KALLIKREIN-KININ SYSTEM IN HOST DEFENCE AGAINST BACTERIAL INFECTIONS.
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批准号:63570167
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项目类别:Grant-in-Aid for General Scientific Research (C)
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资助金额:$1.34万
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财政年份:1988
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负责人:YAMAMOTO Tetsuro
-
依托单位:
PHYLOGENETICAL COMPARISON OF THE CEREBELLO-THALAMO-CORTICAL RESPONSES.
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批准号:62570055
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项目类别:Grant-in-Aid for General Scientific Research (C)
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资助金额:$1.15万
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财政年份:1987
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负责人:YAMAMOTO Tetsuro
-
依托单位:
海外基金