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Establishment of epigenetic pattern during cell differentiation

Establishment of epigenetic pattern during cell differentiation
细胞分化过程中表观遗传模式的建立
批准号:
21591204
负责人:
KITAJIMA Kenji
金额:
$2.91万
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
2009
资助国家:
日本
项目状态:
已结题
起止时间:
2009 至 2011

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中文摘要
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英文摘要
Using mouse embryonic stem cell differentiation induction system, we investigated the role of GATA-1, required for terminal erythroid differentiation, on establishments of erythroid-specific epigenetic pattern. We found that GATA-1 would establish the erythroid-specific epigenetic pattern during cell fate determination from multipotent hematopoietic progenitor cells into erythroid lienage.
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会议论文
iPS細胞から造血幹細胞の誘導
iPS 细胞诱导造血干细胞
DOI: --
发表时间: 2011
期刊: 医学のあゆみ
影响因子: --
作者: [Wada N, et al, Chisako Iriyama, 北島健二,原孝彦]
通讯作者: 北島健二,原孝彦
Long-term repopulation of adult hematopoiesis by in vitro differentiated blood cells from ESCs/iPSCs by LIM homeobox transcription factor, Lhx2
LIM 同源盒转录因子 Lhx2 体外分化的 ESC/iPSC 血细胞对成体造血的长期再增殖
DOI: --
发表时间: 2010
期刊:
影响因子: --
作者: [Kitajima K, Zheng J, Minehata K, Nakano T, Hara T]
通讯作者: Hara T
DOI: 10.1002/jcp.22200
发表时间: 2010-10-01
期刊: JOURNAL OF CELLULAR PHYSIOLOGY
影响因子: 5.6
作者: [Huang, Chien-Ling, Cheng, Ju-Chien, Tseng, Ching-Ping]
通讯作者: Tseng, Ching-Ping
DOI: --
发表时间: 2009
期刊: Exp Hematol
影响因子: 2.6
作者: [Sakai E, Kitajima K, Sato A, Nakano T]
通讯作者: Nakano T
15
    Induction of hematopoietic stem cells from mouse embryonic stem cells by inflammatory cytokines
    Development of novel differentiation induction system of hematopoietic stem cells from human induced pluripotent stem cells
    A study of molecular mechanisms underlying the irreversibility of hematopoieticdifferentiation
    • 批准号:
      19591111
    • 项目类别:
      Grant-in-Aid for Scientific Research (C)
    • 资助金额:
      $2.91万
    • 财政年份:
      2007
    • 负责人:
      KITAJIMA Kenji
    • 依托单位:
    Hematopoietic lineage determination by transcription factors.
    • 批准号:
      16590939
    • 项目类别:
      Grant-in-Aid for Scientific Research (C)
    • 资助金额:
      $2.24万
    • 财政年份:
      2004
    • 负责人:
      KITAJIMA Kenji
    • 依托单位:
    海外基金