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Analysis of genes encoding secretory and membrane protein by CAST method and microRNA regulation in esophago-gastric cancer and its clinical application

Analysis of genes encoding secretory and membrane protein by CAST method and microRNA regulation in esophago-gastric cancer and its clinical application
CAST法及microRNA调控食管胃癌分泌蛋白和膜蛋白基因分析及其临床应用
批准号:
21390105
负责人:
YASUI Wataru
金额:
$11.81万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (B)
财政年份:
2009
资助国家:
日本
项目状态:
已结题
起止时间:
2009 至 2011

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中文摘要
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英文摘要
CAST method was carried out on esophago-gastric cancers and identified DSC2, TSPAN8, TM9SF3, etc. as possible therapeutic target. By microRNA microarray, several microRNAs were identified as diagnostic marker. miR-148a and miR-143 were found to participate in invasion and morphogenesis. New development of diagnosis and therapeutics using novel markers is expected
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会议论文
胃癌におけるolfactomedin 4 の発現と、血清腫瘍マーカーとしての意義
olfactomedin 4在胃癌中的表达及其作为血清肿瘤标志物的意义
DOI: --
发表时间: 2009
期刊:
影响因子: --
作者: [大上直秀, 仙谷和弘, 坂本直也, 安井弥]
通讯作者: 安井弥
Expression of podoplanin/D2-40 in pericryptal stromal cells in superficial colorectal epithelial neoplasia
平足蛋白/D2-40在结直肠浅表上皮肿瘤隐窝周围基质细胞中的表达
DOI: --
发表时间: 2012
期刊: Med Mol Morphol
影响因子: 1.8
作者: [Nakayama H]
通讯作者: Nakayama H
A functional SNP in MUC1, at chromosome 1q22, determines susceptibility to diffuse-type gastric cancer Short title : MUC1 is a gastric cancer susceptibility gene
MUC1 染色体 1q22 上的功能性 SNP 决定了对弥漫型胃癌的易感性 简称:MUC1 是胃癌易感基因
DOI: --
发表时间: 2011
期刊: Gastroenterology
影响因子: 29.4
作者: [Ishikawa Naoshi, et al, 角田俊之, A.Nakai, Saeki N]
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胃癌の発生・進展の分子機序のマイルストーン
胃癌发生和进展的分子机制的里程碑
DOI: --
发表时间: 2011
期刊:
影响因子: --
作者: [岡本竜哉, 他, 安井弥]
通讯作者: 安井弥
98
    nalysis of non-coding RNAs transcribed from ultraconserved regions in digestive tract cancer and its diagnostic and therapeutic application
    • 批准号:
      24659163
    • 项目类别:
      Grant-in-Aid for Challenging Exploratory Research
    • 资助金额:
      $2.5万
    • 财政年份:
      2012
    • 负责人:
      YASUI Wataru
    • 依托单位:
    Protein processing system-regulating microRNA in gastrointestinal carcinogenesis and its clinical application
    • 批准号:
      22659074
    • 项目类别:
      Grant-in-Aid for Challenging Exploratory Research
    • 资助金额:
      $2.02万
    • 财政年份:
      2010
    • 负责人:
      YASUI Wataru
    • 依托单位:
    Functional analysis of gastric cancer-specific genes identified by SAGE data and its clinical implication
    • 批准号:
      17390104
    • 项目类别:
      Grant-in-Aid for Scientific Research (B)
    • 资助金额:
      $9.28万
    • 财政年份:
      2005
    • 负责人:
      YASUI Wataru
    • 依托单位:
    Molecular characterization of gastrointestinal cancer through serial analysis of gene expression and GICHIP and its diagnostic implication
    • 批准号:
      15390116
    • 项目类别:
      Grant-in-Aid for Scientific Research (B)
    • 资助金额:
      $9.79万
    • 财政年份:
      2003
    • 负责人:
      YASUI Wataru
    • 依托单位:
    海外基金