Analysis of the molecules of cell polarity in associated with hormone
Analysis of the molecules of cell polarity in associated with hormone
批准号:
21390443
负责人:
KUBOTA Yoshinobu
金额:
$11.4万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (B)
财政年份:
2009
资助国家:
日本
项目状态:
已结题
起止时间:
2009 至 2011
中文摘要
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英文摘要
The mechanisms of developing hormone refractory prostate cancer(CRPC) remains unclear. We have provided the evidence that aPKCλ/ιexpression correlates with prostate cancer recurrence. Experiments in vitro and in vivo revealed aPKCλ/ιto be involved in prostate cancer cell growth through secretion of IL-6.And we further demonstrated a correlation between biochemical recurrence after prostatectomy and the expression of these two factors. These results support our hypothesis that aPKCλ/ιplay an important role in prostate cancer progression.
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翻訳後修飾のプロテオミクス3章翻訳後修飾解析のための試料調整3.2.組織薄切片からの試料調整
翻译后修饰的蛋白质组学 第 3 章 翻译后修饰分析的样品制备 3.2. 组织薄片样品制备
DOI:
--
发表时间:
2011
期刊:
影响因子:
--
作者:
[秋本和憲, 永坂恵子, 岡山明子, 川上隆雄]
通讯作者:
川上隆雄
Avid F-18 FDG uptake in prostatic sarcoma
前列腺肉瘤中 Avid F-18 FDG 的摄取
DOI:
--
发表时间:
2009
期刊:
Clinical Nuclear Medicine
影响因子:
10.6
作者:
[Minamimoto R, Tateishi U, Uemura H, Yamanaka S, Kubota Y, Inoue T]
通讯作者:
Inoue T
In laterally spreading type tumors(LSTs) of the colon or the rectum, expression of the atypical protein kinase C lambda/iota is correlated to expression of beta-catenin and type IV collagen
在结肠或直肠的横向扩散型肿瘤 (LST) 中,非典型蛋白激酶 C lambda/iota 的表达与 β-连环蛋白和 IV 型胶原蛋白的表达相关
DOI:
--
发表时间:
2010
期刊:
影响因子:
--
作者:
[Ichikawa Y, Ishikawa T, Shimizu D, Goto A, Shimamura T, Suwa H, Tatsumi K, Watanabe K, Ota M, Fujii S, Kawamata M, Akimoto K, Nagashima Y, Takahashi H, Nakajima A, Ohno S, Endo I]
通讯作者:
Endo I
6章翻訳後修飾の機能解析の方法6.8遺伝子操作マウスを用いた個体レベルでの機能解析
第 6 章 翻译后修饰功能分析方法 6.8 使用基因工程小鼠进行个体水平的功能分析
DOI:
--
发表时间:
2011
期刊:
影响因子:
--
作者:
[秋本和憲, 大野茂男]
通讯作者:
大野茂男
Deter mination of Androgens concentrations in prostate tissue taken by needle biopsy by LC/MS/MS. Preliminary study for diagnosis of malignancy from androgen level in prostate tissue
通过 LC/MS/MS 测定针活检采集的前列腺组织中的雄激素浓度。
DOI:
--
发表时间:
2009
期刊:
影响因子:
--
作者:
[Miyoshi Y, Umemoto S, Uemura H, Shibata Y, Arai S, Suzuki K, Honma S, Kubota Y]
通讯作者:
Kubota Y
共 21 条
Development of visible light inducible photocatalytic nano-particles for the diagnosis of bladder cancer
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批准号:25670684
-
项目类别:Grant-in-Aid for Challenging Exploratory Research
-
资助金额:$2.33万
-
财政年份:2013
-
负责人:KUBOTA Yoshinobu
-
依托单位:
A study of measurement in laparoscopic surgery and its reproduction on surgical simulator
-
批准号:23659762
-
项目类别:Grant-in-Aid for Challenging Exploratory Research
-
资助金额:$2.41万
-
财政年份:2011
-
负责人:KUBOTA Yoshinobu
-
依托单位:
Analysis of cell polarity associated molecules in prostate cancer for the application to diagnosis and treatment
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批准号:17390442
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$10.05万
-
财政年份:2005
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负责人:KUBOTA Yoshinobu
-
依托单位:
Analysis and detection of the molecules involving hormone refractory prostate cancer by applying Proteomics methodology
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批准号:14370517
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$9.15万
-
财政年份:2002
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负责人:KUBOTA Yoshinobu
-
依托单位:
Technological study for medical application of TiO_2 photocatalysis
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批准号:14050083
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项目类别:Grant-in-Aid for Scientific Research on Priority Areas
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资助金额:$36.54万
-
财政年份:2001
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负责人:KUBOTA Yoshinobu
-
依托单位:
Study of the identification of new genes inducing hormone refractory prostate cancer
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批准号:11470339
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$3.46万
-
财政年份:1999
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负责人:KUBOTA Yoshinobu
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依托单位:
Study of the development a new type of treatment of urogenital cancer by using surface modified fine metal particles.
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批准号:10557143
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项目类别:Grant-in-Aid for Scientific Research (B)
-
资助金额:$3.97万
-
财政年份:1998
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负责人:KUBOTA Yoshinobu
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依托单位:
Study of the Identification of new genes associated with development and recurrence of prostate cancer
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批准号:08457428
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$4.22万
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财政年份:1996
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负责人:KUBOTA Yoshinobu
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依托单位:
Analysis of genes involving in reactivation of prostate cancer
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批准号:06454460
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项目类别:Grant-in-Aid for General Scientific Research (B)
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资助金额:$2.56万
-
财政年份:1994
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负责人:KUBOTA Yoshinobu
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依托单位:
Application of photoexcited TiO2 semicondoctor to the treatment of bladder cancer
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批准号:05557071
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项目类别:Grant-in-Aid for Developmental Scientific Research (B)
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资助金额:$3.97万
-
财政年份:1993
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负责人:KUBOTA Yoshinobu
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依托单位:
Analysis of the genes involved in the growth of human professor
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批准号:03454388
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项目类别:Grant-in-Aid for General Scientific Research (B)
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资助金额:$2.5万
-
财政年份:1991
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负责人:KUBOTA Yoshinobu
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依托单位:
Development of a new cancer therapy using photoexcited semiconductor particles
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批准号:01870069
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项目类别:Grant-in-Aid for Developmental Scientific Research (B).
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资助金额:$3.39万
-
财政年份:1989
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负责人:KUBOTA Yoshinobu
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依托单位:
Phosphatidylinositol turnover of cancer cell menbrane and development of new treatment of renal cell carcinoma
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批准号:61570771
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项目类别:Grant-in-Aid for General Scientific Research (C)
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资助金额:$1.54万
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财政年份:1986
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负责人:KUBOTA Yoshinobu
-
依托单位: