Development of surveillance tools for eradication of schistosomiasis japonica applicable for the endemic areas in China

适用于中国流行地区的日本血吸虫病消灭监测工具的开发

• 批准号: 21406008
• 负责人: OHTA Nobuo
• 金额: $ 10.57万
• 依托单位: Tokyo Medical and Dental University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (B)
• 财政年份: 2009
• 资助国家: 日本
• 起止时间: 2009 至 2011
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-21406008/
• 关键词: 蠕虫; 日本住血吸虫; DNA診断; LAMP; Oncomelania; 遺伝子診断; LAMP法; PCR法; 疾病対策; GPS; PCR

New surveillance tools for schistosomiasis control were developed and tested in endemic foci in China. LAMP method was confirmed to be an easy method of high sensitivity and specificity, which could be applied for on-site use without special equipments. Together with those simple and reliable tools, epidemiological surveillance using GIS for evaluating risk factors of bleeding snail hosts should be introduced especially for big endemic fields like those in China. By the use of those new tools, more effective strategy for eliminating schistosomiasis japonica was proposed for endemic foci in China.

开发了新的血吸虫病监测工具，并在中国血吸虫病流行区进行了试验。LAMP方法具有灵敏度高、特异性强、操作简便、无需特殊仪器设备等优点，可在现场应用。在这些简单可靠的工具的基础上，应引入GIS进行流行病学监测，以评估出血性钉螺宿主的危险因素，特别是在中国这样的大流行区。利用这些新工具，为我国血吸虫病疫源地的消灭提供了更有效的策略。

项目成果

Schistosomiasis research in Japan Overview of current situation.

日本血吸虫病研究现状概况。

• 发表时间: 2010
• 作者: Yaguchi T;Matsuzawa T;Tanaka R;Abliz P;Hui Y;Horie Y;Ohta N.
• 通讯作者: Ohta N.

日本における伝染病との闘いの歴史(菅又昌実編著)

日本抗击传染病的历史（菅俣正美编）

• 发表时间: 2010
• 作者: 太田伸生;保阪幸男
• 通讯作者: 保阪幸男

IL-4/IL-13 suppress excessive granulomatous inflammation in schistosomiasis japonica

IL-4/IL-13抑制日本血吸虫病过度肉芽肿性炎症

• 发表时间: 2011
• 作者: Seki T;Kumagai T;Kwansa-Bentum B;Furushima-Shimogawara R;AnyanWK;Miyazawa Y;Iwakura Y;Ohta N
• 通讯作者: Ohta N

Schistosomiasis research in Japan : Overview of current situation

日本血吸虫病研究：现状概述

• 发表时间: 2010
• 作者: 真田崇弘;ら;Ohta N
• 通讯作者: Ohta N

Using ALOS satellite images to develop efficient measures against vector-borne diseases-egional differences in outbreak risk for schistosomiasis japonica in China

利用ALOS卫星影像制定有效防治媒介传播疾病的措施——中国日本血吸虫病暴发风险的区域差异

• 发表时间: 2010
• 作者: Nihei N;Komagata O;Kobayashi M;Ohta N;Saitoh Y;Mochizuki K;Chen R;Lu SH;Wen LY;Wang TP
• 通讯作者: Wang TP