Identification and functional analysis of the sensor system involved in behavioral regulation of larvae of digenic platyhelminthes.

点击翻译按钮获取中文摘要

In the hope of uncovering sensor system of digenic platyhelminthes, we analyzed possible sensor organs of cercariae Schistosoma manosin. Cercariae of S. manosini were strongly attracted by linoleic acid and the responsible sensor seemed to be detected on the surface of cercariae. It was needed to test the direct effects of the probable sensors, and RNAi was applied for schistosoma cercariae. There are still technical matters left for RNAi at the cercarial stage. Results of the current study seem to lead development of reagents to avoid schistosomal infection targeting the skin penatration of cercariae.