Detection and identification of Candida species in oral mucosal lesions for new oral care treatment

点击翻译按钮获取中文摘要

Candida species were detected and identified in samples from the buccal mucosa, dorsal surface of the tongue and supragingival plaque of subjects with oral lichen planus(OLP). The Candida in the samples were cultured on selection agars, and identified by sequence analyses of 18S, 5. 8S and 25/28S rRNA. The isolation frequency of Candida was higher in subjects with OLP than in those with healthy oralmucosa. Non-C. albicans were only isolated from people with OLP. These results support the notion that subjects with OLP are more likely to have oral colonization with Candida, and that non-C. albicans are specifically present in subjects with this condition.