Elucidation ofpathogenesis and establishment of objective assessment for intraocular pressure-dependent optic nerve damage
Elucidation ofpathogenesis and establishment of objective assessment for intraocular pressure-dependent optic nerve damage
批准号:
22390324
负责人:
NEGI Akira
金额:
$9.82万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (B)
财政年份:
2010
资助国家:
日本
项目状态:
已结题
起止时间:
2010 至 2012
中文摘要
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英文摘要
The degree of visual field defect in glaucomatous patients correlated with postural fluctuation of intraocular pressure. Optimal conditions for multi-channel, multifocal visual evoked potential (mfVEP) recordings were established. Visual dysfunction in glaucomatous damages was objectively detected by quantitative analysis of mfVEP global index we have developed. We found that astrocytes in the optic nerve and retinal ganglion cells express aquaporin 9 water channel and that glaucoma and optic nerve crush injuries decrease it.
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緑内障性視神経症への挑戦.その基礎と臨床における三つの仮説の提唱
青光眼视神经病变的挑战。
DOI:
--
发表时间:
2011
期刊:
影响因子:
--
作者:
[Ishikawa K, Yoshida S, Nakao S, Nakama T, Kita T, Asato R, Sassa Y, Arita R, Miyazaki M, Enaida H, Oshima Y, Murakami N, Niiro H, Ono J, Matsuda A, Goto Y, Akashi K, Izuhara K, Kudo A, Kono T, Hafezi-Moghadam A, and Ishibashi T, 中村 誠]
通讯作者:
中村 誠
視神経疾患の新しい展開
视神经疾病的新进展
DOI:
--
发表时间:
2012
期刊:
影响因子:
--
作者:
[山岸麗子, 相原一, 新家眞, 坪田一男, Kumai Y, 吉川裕之, 根木 昭]
通讯作者:
根木 昭
The role of aquaporin in glaucomatous optic neuropathy
水通道蛋白在青光眼性视神经病变中的作用
DOI:
--
发表时间:
2010
期刊:
影响因子:
--
作者:
[Yamanari M, Ishii K, Miura M, Oshika T, Yasuno Y, Makoto Nakamura]
通讯作者:
Makoto Nakamura
多局所視覚誘発電位の受信者操作特性曲線解析に及ぼす高度近視の影響
高度近视对多局部视觉诱发电位受试者工作特征曲线分析的影响
DOI:
--
发表时间:
2012
期刊:
影响因子:
--
作者:
[加藤 慶, 鎌田誠子, 田渕久美子, 中村 誠, 根木 昭.]
通讯作者:
根木 昭.
Objective Functional assessment in Glaucoma
青光眼的客观功能评估
DOI:
--
发表时间:
2012
期刊:
影响因子:
--
作者:
[Ji-Ae Ko, Chihiro Ohki, Tai-ichiro Chikama, Yoshiaki Kiuchi, Makoto Nakamura]
通讯作者:
Makoto Nakamura
共 10 条
Elucidation of association between retinal ganglion cell death and extracellular matrix in various models of optic nerve degeneration
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批准号:19390444
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$7.57万
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财政年份:2007
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负责人:NEGI Akira
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依托单位:
Analysis of aberrant retinal neuro-glial relationship in glaucoma and diabetic retinopathy
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批准号:16390499
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$5.18万
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财政年份:2004
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负责人:NEGI Akira
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依托单位:
Analysis of intraretinal neuro-glial interaction in glaucoma
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批准号:14571672
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.37万
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财政年份:2002
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负责人:NEGI Akira
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依托单位:
Studies on the mechanisms of sensory retinal adhesion, its breakdown and reconstruction
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批准号:11671746
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$1.02万
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财政年份:1999
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负责人:NEGI Akira
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依托单位:
INVESTIGATION ABOUT THE MECHANISM OF RETINAL ADHESION AND ITS BREAKDOWN AND RECOVERY
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批准号:07457413
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$4.8万
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财政年份:1995
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负责人:NEGI Akira
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依托单位:
海外基金