Study about pathogenic, environmental, and social factors of oral health in adult population by comparing Japan and South Korea

一项关于口腔健康的全国性调查的比较表明，韩国人口的牙周健康状况比日本好，尽管他们有相似的固有背景。在这里，我们调查了韩国和日本口腔健康成人之间的口腔细菌组合的差异。与韩国受试者相比，日本受试者的微生物群包括更多样化的群落，17个细菌属的比例更高，包括韦荣氏球菌、梭杆菌和普雷沃氏菌。相反，奈瑟菌和嗜血杆菌在日本受试者的微生物群中的比例要低得多。由于在我们之前的研究中，较高比例的普雷沃菌和韦荣球菌以及较低比例的奈瑟菌与牙周炎有关，因此本研究的结果表明，日本受试者口腔微生物群中的较大比例与其对牙周炎的较高易感性有关。

A comparison of national surveys on oral health suggested that the population of South Korea has better periodontal health status than that of Japan, despite their similar inherent background. Here, we investigated differences in oral bacterial assemblages between Korean and Japanese orally healthy adults. The microbiota of Japanese subjects comprised a more diverse community, with higher proportions of 17 bacterial genera, including Veillonella, Fusobacterium and Prevotella, as compared with those of Korean subjects. Conversely, Neisseria and Haemophilus species were present in much lower proportions in the microbiota of Japanese subjects. Because higher proportions of Prevotella and Veillonella and a lower proportion of Neisseria were implicated in periodontitis in our previous study, the results of this study suggest that the greater proportion of dysbiotic oral microbiota in the Japanese subjects is related to their higher susceptibility to periodontitis.