Comprehensive analysis of neural differentiation programs in the neural circuit formation
Comprehensive analysis of neural differentiation programs in the neural circuit formation
批准号:
22500295
负责人:
ONO Katsuhiko
金额:
$2.83万
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
2010
资助国家:
日本
项目状态:
已结题
起止时间:
2010 至 2012
中文摘要
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英文摘要
To understand mechanisms underlying neural circuit formation, we analyzed Olig2 function on the diencephalon formation including thalamocortical projection formation. Olig2 deficient mouse shows malformation (reduced size) of the prethalamus and expansion of the thalamic eminence. In addition, thalamocortical axons follow tortuous courses. The prethalamus has long been regarded as an intermediate target for the thalamocortical projection formation. Our results indicate that Olig2 regulates prethalamus formation, and also thalamocortical projection formation with an indirect manner. These results have been submitted to Development, an international journal for developmental biology, and now under revision.
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Distribution of corticosteroid receptors in oligodendrocytes of mice
小鼠少突胶质细胞皮质类固醇受体的分布
DOI:
--
发表时间:
2013
期刊:
影响因子:
--
作者:
[MatsusueY, Horii-Hayashi N, Sasagawa T, Matsunaga W, Ono K, Nishi M]
通讯作者:
Nishi M
Generation of somatic motoneurons from Nkx2.2-expressing progenitor cells in chick embryonic spinal cord.
鸡胚脊髓中表达 Nkx2.2 的祖细胞产生体细胞运动神经元。
DOI:
--
发表时间:
2012
期刊:
影响因子:
--
作者:
[Kai N, Tsutsui Y, Kobayashi K, Ono K,, Gotoh H,]
通讯作者:
Gotoh H,
DOI:
10.1371/journal.pone.0051581
发表时间:
2012
期刊:
PloS one
影响因子:
3.7
作者:
[Gotoh H, Ono K, Nomura T, Takebayashi H, Harada H, Nakamura H, Ikenaka K]
通讯作者:
Ikenaka K
DOI:
10.1002/cne.22319
发表时间:
2010-06
期刊:
Journal of Comparative Neurology
影响因子:
2.5
作者:
[S. Murakami;H. Ohki‐Hamazaki;Keisuke Watanabe;K. Ikenaka;K. Ono]
通讯作者:
S. Murakami;H. Ohki‐Hamazaki;Keisuke Watanabe;K. Ikenaka;K. Ono
Involvement of Olig2 in the formation of reciprocal connection between the thalamus and cortex
Olig2 参与丘脑和皮质之间相互连接的形成
DOI:
--
发表时间:
2013
期刊:
影响因子:
--
作者:
[Ono K, Parras CM, Nomura T, Zhang Q, Takebayashi H, Shimamura K, Gotoh H, Itohara S, Ikenaka K]
通讯作者:
Ikenaka K
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