oles of orexin neuron on the reward based spontaneous voluntary behavior

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To understand the role of the striatum in value- and strategy-based decision-making and hypothalamic orexin neuron in reward based spontaneous ehavior, we recorded striatal and the orexin neurons in macaque monkeys and rats Large subsets of striatal neurons encoded positive and negative outcome feedbacks of individual decisions and actions. Juxtacellular recording was made in hypothalamic area and investigate orexin neuron by means of immunohistochemical method. This sample is presently being analyzed. These activity profiles as a heterogeneous representation of decision variables may underlie a part of the process for reinforcement- and strategy-based evaluation of selected actions in the striatum.