Development of an osteoporosis prevention program involving metabolic syndrome correction in middle-aged to elderly females

研究对象包括83名连续接受调查的女性居民。如前所述，在潜在肥胖组中，足跟骨密度和瘦素水平明显高于瘦和正常组，而E2水平明显低于瘦和正常组。这些结果表明，瘦/正常中年女性的肠道钙吸收受遗传影响，而脂肪细胞中的瘦素有助于维持体脂率高的潜在肥胖/肥胖中年至老年女性的骨矿物质密度。

The subjects consisted of 83 female residents who had been continuously investigated. In the latently obese group, the heel bone mineral density and leptin level were significantly higher than in the thin and normal groups, as previously reported, whereas the E2 level was significantly lower. These results suggest that Ca absorption in the intestinal tract is genetically influenced in thin/normal middle-aged females, whereas leptin in adipose cells contributes to the maintenance of the bone mineral density in latently obese/obese middle-aged to elderly females with a high percent body fat.