Development of a new cancer chemotherapy by using curcumin analogs

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We have developed 86 types of new curcumin analogs, successfully resulting in getting several analogs with higher anti-cancer potential. These analogs are effective for various cancers including colorectal cancer stem cells. They are shown to be NF-κB inhibitors. In animal models, they were also shown to be effective for some cancers such as gastric cancers and colorectal cancer stem cells. These data indicate that new curcumin analogs have some potential to treat cancers.