Studies on the overexpression of insect cytochrome P450s for the molecular identification of insecticide resistance
Studies on the overexpression of insect cytochrome P450s for the molecular identification of insecticide resistance
批准号:
22580064
负责人:
TOMITA Takashi
金额:
$2.83万
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
2010
资助国家:
日本
项目状态:
已结题
起止时间:
2010 至 2012
中文摘要
研究了致倦库蚊细胞色素P450基因的过表达及其与幼虫和成虫对拟除虫菊酯抗性的关系。我们证明了由于顺式作用突变导致的CYP9M10的过度表达至少在全球范围内与该物种的幼虫对拟除虫菊酯的代谢抗性有关,并建立了一种鉴定过度表达的CYP9M10单倍型的分子基因分型方法。
英文摘要
Cytochrome P450 genes genetically overexpressing and associated with each of larval and adult pyrethroid resistance in Culex quinquefasciatus were studied. We demonstrated that the overexpression of CYP9M10 due to cis-acting mutations is globally addressed to at least larval metabolic resistance to pyrethroids in this species and established a molecular genotyping method for identifying overexpressing CYP9M10 haplotypes.
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Genetic variability of Culex Cyp9m10 and insecticide susceptibility
库蚊 Cyp9m10 的遗传变异和杀虫剂敏感性
DOI:
--
发表时间:
2012
期刊:
影响因子:
--
作者:
[Itokawa, K., Komagata, O., Kasai, S., Tomita, T]
通讯作者:
T
DOI:
10.1016/j.ibmb.2011.04.002
发表时间:
2011-07-01
期刊:
INSECT BIOCHEMISTRY AND MOLECULAR BIOLOGY
影响因子:
3.8
作者:
[Itokawa, Kentaro, Komagata, Osamu, Tomita, Takashi]
通讯作者:
Tomita, Takashi
殺虫剤抵抗性CYP9M10ハプロタイプの分子進化と拡散
抗杀虫剂CYP9M10单倍型的分子进化和传播
DOI:
--
发表时间:
2012
期刊:
影响因子:
--
作者:
[糸川健太郎, 駒形修, 葛西真治, 川田均, 冨田隆史]
通讯作者:
冨田隆史
ネッタイイエカCYP9M10 遺伝子の分子進化とピレスロイド抵抗性
埃及伊蚊CYP9M10基因的分子进化和拟除虫菊酯抗性
DOI:
--
发表时间:
2011
期刊:
影响因子:
--
作者:
[糸川健太郎, 駒形修, 葛西真治, 川田均, 岡村佳香, 政田正弘, 冨田隆史]
通讯作者:
冨田隆史
害虫の殺虫剤抵抗性機構
害虫的抗药性机制
DOI:
--
发表时间:
2013
期刊:
影响因子:
--
作者:
[新垣則雄, 外間康洋, 永山敦士, 安藤緑樹, 谷崎樹生, 村路雅彦, 安居拓恵, 若村定男, 秋野順治, 平井剛夫, 冨田隆史]
通讯作者:
冨田隆史
共 10 条
Genetic study on overexpression mechanisms of cytochrome P450 in insecticide resistant insect
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批准号:19580062
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项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$2.91万
-
财政年份:2007
-
负责人:TOMITA Takashi
-
依托单位:
The identification of Cytochrome P450s involved in the biosynthesis of ecdysteroid hormon and their gene expression systems
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批准号:14560046
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.3万
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财政年份:2002
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负责人:TOMITA Takashi
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依托单位:
Genetic and biochemical analysis of insecticide-insensitivity of acetylcholinesterase in vector mosquitoes
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批准号:10670246
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.05万
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财政年份:1998
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负责人:TOMITA Takashi
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依托单位:
Cloning of insecticide resistant genes based on conserved peptide sequences
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批准号:07660067
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$1.34万
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财政年份:1995
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负责人:TOMITA Takashi
-
依托单位:
海外基金